Antigenic Variation

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"Antigenic Variation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Change in the surface ANTIGEN of a microorganism. There are two different types. One is a phenomenon, especially associated with INFLUENZA VIRUSES, where they undergo spontaneous variation both as slow antigenic drift and sudden emergence of new strains (antigenic shift). The second type is when certain PARASITES, especially trypanosomes, PLASMODIUM, and BORRELIA, survive the immune response of the host by changing the surface coat (antigen switching). (From Herbert et al., The Dictionary of Immunology, 4th ed)

Descriptor ID	D000940
MeSH Number(s)	G05.365.073 G12.500.249
Concept/Terms	Antigenic Variation Antigenic Variation Antigenic Variability Variability, Antigenic Variation, Antigenic Antigen Variation Variation, Antigen Antigenic Diversity Antigenic Diversity Diversity, Antigenic Antigen Switching Antigen Switching Switching, Antigen Switching, Antigenic Antigenic Switching

Below are MeSH descriptors whose meaning is more general than "Antigenic Variation".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Variation [G05.365]
Antigenic Variation [G05.365.073]
Immune System Phenomena [G12]
Immunogenetic Phenomena [G12.500]
Antigenic Variation [G12.500.249]

Below are MeSH descriptors whose meaning is related to "Antigenic Variation".

Below are MeSH descriptors whose meaning is more specific than "Antigenic Variation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antigenic Variation" by people in this website by year, and whether "Antigenic Variation" was a major or minor topic of these publications.

Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 1995 and 2009 and 2012 and 2017 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
2009	0	1	1
2012	0	1	1
2017	1	0	1
2021	0	1	1

Below are the most recent publications written about "Antigenic Variation" by people in Profiles.

Kunze KL, Johnson PW, van Helmond N, Senefeld JW, Petersen MM, Klassen SA, Wiggins CC, Klompas AM, Bruno KA, Mills JR, Theel ES, Buras MR, Golafshar MA, Sexton MA, Diaz Soto JC, Baker SE, Shepherd JRA, Verdun NC, Marks P, Paneth NS, Fairweather D, Wright RS, van Buskirk CM, Winters JL, Stubbs JR, Senese KA, Pletsch MC, Buchholtz ZA, Rea RF, Herasevich V, Whelan ER, Clayburn AJ, Larson KF, Ripoll JG, Andersen KJ, Lesser ER, Vogt MNP, Dennis JJ, Regimbal RJ, Bauer PR, Blair JE, Casadevall A, Carter RE, Joyner MJ. Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors. Nat Commun. 2021 08 11; 12(1):4864.

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Kandeil A, El-Shesheny R, Maatouq A, Moatasim Y, Cai Z, McKenzie P, Webby R, Kayali G, Ali MA. Novel reassortant H9N2 viruses in pigeons and evidence for antigenic diversity of H9N2 viruses isolated from quails in Egypt. J Gen Virol. 2017 Apr; 98(4):548-562.

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El-Shesheny R, Kayali G, Kandeil A, Cai Z, Barakat AB, Ghanim H, Ali MA. Antigenic diversity and cross-reactivity of avian influenza H5N1 viruses in Egypt between 2006 and 2011. J Gen Virol. 2012 Dec; 93(Pt 12):2564-74.

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Sealy R, Slobod KS, Flynn P, Branum K, Surman S, Jones B, Freiden P, Lockey T, Howlett N, Hurwitz JL. Preclinical and clinical development of a multi-envelope, DNA-virus-protein (D-V-P) HIV-1 vaccine. Int Rev Immunol. 2009; 28(1):49-68.

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Baruch DI, Pasloske BL, Singh HB, Bi X, Ma XC, Feldman M, Taraschi TF, Howard RJ. Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes. Cell. 1995 Jul 14; 82(1):77-87.

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Dietzschold B, Rupprecht CE, Tollis M, Lafon M, Mattei J, Wiktor TJ, Koprowski H. Antigenic diversity of the glycoprotein and nucleocapsid proteins of rabies and rabies-related viruses: implications for epidemiology and control of rabies. Rev Infect Dis. 1988 Nov-Dec; 10 Suppl 4:S785-98.

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Dietzschold B, Tollis M, Rupprecht CE, Celis E, Koprowski H. Antigenic variation in rabies and rabies-related viruses: cross-protection independent of glycoprotein-mediated virus-neutralizing antibody. J Infect Dis. 1987 Nov; 156(5):815-22.

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