Somatic Hypermutation, Immunoglobulin
"Somatic Hypermutation, Immunoglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A programmed mutation process whereby changes are introduced to the nucleotide sequence of immunoglobulin gene DNA during development.
| Descriptor ID |
D027041
|
| MeSH Number(s) |
G05.558.810 G12.500.780
|
| Concept/Terms |
Somatic Hypermutation, Immunoglobulin- Somatic Hypermutation, Immunoglobulin
- Hypermutation, Immunoglobulin Somatic
- Hypermutations, Immunoglobulin Somatic
- Immunoglobulin Somatic Hypermutations
- Somatic Hypermutations, Immunoglobulin
- Ig Somatic Hypermutation
- Immunoglobulin Somatic Hypermutation
- Hypermutation, Somatic, Immunoglobulin
- Somatic Hypermutation, Ig
- Hypermutation, Ig Somatic
- Hypermutations, Ig Somatic
- Ig Somatic Hypermutations
- Somatic Hypermutations, Ig
|
Below are MeSH descriptors whose meaning is more general than "Somatic Hypermutation, Immunoglobulin".
Below are MeSH descriptors whose meaning is more specific than "Somatic Hypermutation, Immunoglobulin".
This graph shows the total number of publications written about "Somatic Hypermutation, Immunoglobulin" by people in this website by year, and whether "Somatic Hypermutation, Immunoglobulin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 1 | 2 |
| 2007 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Somatic Hypermutation, Immunoglobulin" by people in Profiles.
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Domeier PP, Schell SL, Rahman ZS. Spontaneous germinal centers and autoimmunity. Autoimmunity. 2017 Feb; 50(1):4-18.
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Alabyev B, Rahman ZS, Manser T. Quantitatively reduced participation of anti-nuclear antigen B cells that down-regulate B cell receptor during primary development in the germinal center/memory B cell response to foreign antigen. J Immunol. 2007 May 01; 178(9):5623-34.
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Rahman ZS, Alabyev B, Manser T. FcgammaRIIB regulates autoreactive primary antibody-forming cell, but not germinal center B cell, activity. J Immunol. 2007 Jan 15; 178(2):897-907.
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Alabyev B, Manser T. Bcl-2 rescues the germinal center response but does not alter the V gene somatic hypermutation spectrum in MSH2-deficient mice. J Immunol. 2002 Oct 01; 169(7):3819-24.
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Notidis E, Heltemes L, Manser T. Dominant, hierarchical induction of peripheral tolerance during foreign antigen-driven B cell development. Immunity. 2002 Sep; 17(3):317-27.
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Notidis E, Hande S, Manser T. Enforced expression of Bcl-2 selectively perturbs negative selection of dual reactive antibodies. Dev Immunol. 2001; 8(3-4):223-34.