"Biotransformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.
| Descriptor ID |
D001711
|
| MeSH Number(s) |
G03.171 G03.787.225 G07.690.725.225
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Biotransformation".
Below are MeSH descriptors whose meaning is more specific than "Biotransformation".
This graph shows the total number of publications written about "Biotransformation" by people in this website by year, and whether "Biotransformation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 3 | 3 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 4 | 4 |
| 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Biotransformation" by people in Profiles.
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Krotulski AJ, Papsun DM, Noble C, Kacinko SL, Logan BK. Brorphine-Investigation and quantitation of a new potent synthetic opioid in forensic toxicology casework using liquid chromatography-mass spectrometry. J Forensic Sci. 2021 Mar; 66(2):664-676.
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Presley BC, Logan BK, Jansen-Varnum SA. In Vitro Metabolic Profile Elucidation of Synthetic Cannabinoid APP-CHMINACA (PX-3). J Anal Toxicol. 2020 Apr 30; 44(3):226-236.
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Krotulski AJ, Mohr ALA, Papsun DM, Logan BK. Dibutylone (bk-DMBDB): Intoxications, Quantitative Confirmations and Metabolism in Authentic Biological Specimens. J Anal Toxicol. 2018 Sep 01; 42(7):437-445.
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Krotulski AJ, Papsun DM, De Martinis BS, Mohr ALA, Logan BK. N-Ethyl Pentylone (Ephylone) Intoxications: Quantitative Confirmation and Metabolite Identification in Authentic Human Biological Specimens. J Anal Toxicol. 2018 Sep 01; 42(7):467-475.
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Davis JD, Bansal A, Hassman D, Akinlade B, Li M, Li Z, Swanson B, Hamilton JD, DiCioccio AT. Evaluation of Potential Disease-Mediated Drug-Drug Interaction in Patients With Moderate-to-Severe Atopic Dermatitis Receiving Dupilumab. Clin Pharmacol Ther. 2018 12; 104(6):1146-1154.
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Krotulski AJ, Papsun DM, Friscia M, Swartz JL, Holsey BD, Logan BK. Fatality Following Ingestion of Tetrahydrofuranylfentanyl, U-49900 and Methoxy-Phencyclidine. J Anal Toxicol. 2018 Apr 01; 42(3):e27-e32.
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Franasiak JM, Barnett R, Molinaro TA, Gabriele D, Gartmond TD, Treff NR, Scott RT. CYP1A1 3801T>C polymorphism implicated in altered xenobiotic metabolism is not associated with?variations in sperm production and function as measured by total motile sperm and fertilization rates with intracytoplasmic sperm injection. Fertil Steril. 2016 08; 106(2):481-6.
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Castaneto MS, Wohlfarth A, Desrosiers NA, Hartman RL, Gorelick DA, Huestis MA. Synthetic cannabinoids pharmacokinetics and detection methods in biological matrices. Drug Metab Rev. 2015 May; 47(2):124-74.
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Ropero-Miller JD, Huestis MA, Stout PR. Cocaine analytes in human hair: evaluation of concentration ratios in different cocaine sources, drug-user populations and surface-contaminated specimens. J Anal Toxicol. 2012 Jul; 36(6):390-8.
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Schwope DM, Bosker WM, Ramaekers JG, Gorelick DA, Huestis MA. Psychomotor performance, subjective and physiological effects and whole blood ??-tetrahydrocannabinol concentrations in heavy, chronic cannabis smokers following acute smoked cannabis. J Anal Toxicol. 2012 Jul; 36(6):405-12.