Bromodeoxyuridine

"Bromodeoxyuridine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.

Descriptor ID	D001973
MeSH Number(s)	D03.383.742.680.852.300.150 D13.570.230.430.196 D13.570.685.852.300.150
Concept/Terms	Bromodeoxyuridine Bromodeoxyuridine Bromouracil Deoxyriboside Deoxyriboside, Bromouracil 5-Bromo-2'-deoxyuridine 5 Bromo 2' deoxyuridine BrdU BUdR 5-Bromodeoxyuridine 5 Bromodeoxyuridine Broxuridine NSC-38297 NSC-38297

Below are MeSH descriptors whose meaning is more general than "Bromodeoxyuridine".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Pyrimidines [D03.383.742]
Pyrimidine Nucleosides [D03.383.742.680]
Uridine [D03.383.742.680.852]
Deoxyuridine [D03.383.742.680.852.300]
Bromodeoxyuridine [D03.383.742.680.852.300.150]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleosides [D13.570]
Deoxyribonucleosides [D13.570.230]
Deoxyuridine [D13.570.230.430]
Bromodeoxyuridine [D13.570.230.430.196]
Pyrimidine Nucleosides [D13.570.685]
Uridine [D13.570.685.852]
Deoxyuridine [D13.570.685.852.300]
Bromodeoxyuridine [D13.570.685.852.300.150]

Below are MeSH descriptors whose meaning is related to "Bromodeoxyuridine".

Below are MeSH descriptors whose meaning is more specific than "Bromodeoxyuridine".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bromodeoxyuridine" by people in this website by year, and whether "Bromodeoxyuridine" was a major or minor topic of these publications.

Bar chart showing 16 publications over 9 distinct years, with a maximum of 5 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2003	1	0	1
2004	0	2	2
2005	0	5	5
2006	0	1	1
2007	0	1	1
2008	0	2	2
2010	0	2	2
2012	0	1	1

Below are the most recent publications written about "Bromodeoxyuridine" by people in Profiles.

Rivetti di Val Cervo P, Lena AM, Nicoloso M, Rossi S, Mancini M, Zhou H, Saintigny G, Dellambra E, Odorisio T, Mahé C, Calin GA, Candi E, Melino G. p63-microRNA feedback in keratinocyte senescence. Proc Natl Acad Sci U S A. 2012 Jan 24; 109(4):1133-8.

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Bussard KM, Boulanger CA, Kittrell FS, Behbod F, Medina D, Smith GH. Immortalized, pre-malignant epithelial cell populations contain long-lived, label-retaining cells that asymmetrically divide and retain their template DNA. Breast Cancer Res. 2010; 12(5):R86.

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Fang M, Sigal L. Studying NK cell responses to ectromelia virus infections in mice. Methods Mol Biol. 2010; 612:411-28.

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McLennan GP, Kiss A, Miyatake M, Belcheva MM, Chambers KT, Pozek JJ, Mohabbat Y, Moyer RA, Bohn LM, Coscia CJ. Kappa opioids promote the proliferation of astrocytes via Gbetagamma and beta-arrestin 2-dependent MAPK-mediated pathways. J Neurochem. 2008 Dec; 107(6):1753-65.

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Magnus T, Carmen J, Deleon J, Xue H, Pardo AC, Lepore AC, Mattson MP, Rao MS, Maragakis NJ. Adult glial precursor proliferation in mutant SOD1G93A mice. Glia. 2008 Jan 15; 56(2):200-8.

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Wan H, South AP, Hart IR. Increased keratinocyte proliferation initiated through downregulation of desmoplakin by RNA interference. Exp Cell Res. 2007 Jul 01; 313(11):2336-44.

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Hassan GS, Mukherjee S, Nagajyothi F, Weiss LM, Petkova SB, de Almeida CJ, Huang H, Desruisseaux MS, Bouzahzah B, Pestell RG, Albanese C, Christ GJ, Lisanti MP, Tanowitz HB. Trypanosoma cruzi infection induces proliferation of vascular smooth muscle cells. Infect Immun. 2006 Jan; 74(1):152-9.

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Li J, Hassan GS, Williams TM, Minetti C, Pestell RG, Tanowitz HB, Frank PG, Sotgia F, Lisanti MP. Loss of caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation. Cell Cycle. 2005 Dec; 4(12):1817-25.

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Coksaygan T, Magnus T, Cai J, Mughal M, Lepore A, Xue H, Fischer I, Rao MS. Neurogenesis in Talpha-1 tubulin transgenic mice during development and after injury. Exp Neurol. 2006 Feb; 197(2):475-85.

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Smeyne M, Jiao Y, Shepherd KR, Smeyne RJ. Glia cell number modulates sensitivity to MPTP in mice. Glia. 2005 Nov 1; 52(2):144-52.

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