Cholinesterase Inhibitors
"Cholinesterase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
| Descriptor ID |
D002800
|
| MeSH Number(s) |
D27.505.519.389.275 D27.505.519.625.120.300 D27.505.696.577.120.300
|
| Concept/Terms |
Cholinesterase Inhibitors- Cholinesterase Inhibitors
- Inhibitors, Cholinesterase
- Anticholinesterase Drugs
- Drugs, Anticholinesterase
- Anticholinesterases
- Anticholinesterase Agents
- Agents, Anticholinesterase
- Anti-Cholinesterases
- Anti Cholinesterases
|
Below are MeSH descriptors whose meaning is more general than "Cholinesterase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Cholinesterase Inhibitors".
This graph shows the total number of publications written about "Cholinesterase Inhibitors" by people in this website by year, and whether "Cholinesterase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cholinesterase Inhibitors" by people in Profiles.
-
Fink HA, Jutkowitz E, McCarten JR, Hemmy LS, Butler M, Davila H, Ratner E, Calvert C, Barclay TR, Brasure M, Nelson VA, Kane RL. Pharmacologic Interventions to Prevent Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer-Type Dementia: A Systematic Review. Ann Intern Med. 2018 01 02; 168(1):39-51.
-
Stefanacci RG. The costs of Alzheimer's disease and the value of effective therapies. Am J Manag Care. 2011 Nov; 17 Suppl 13:S356-62.
-
Irwin D, Lippa CF, Rosso A. Effects of prescribed medications on cognition and behavior in frontotemporal lobar degeneration. Am J Alzheimers Dis Other Demen. 2010 Nov; 25(7):566-71.
-
Lippa CF. Interventions and diagnostics in Alzheimer's disease and related conditions. Am J Alzheimers Dis Other Demen. 2010 Mar; 25(2):107-8.
-
Samanta U, Kirby SD, Srinivasan P, Cerasoli DM, Bahnson BJ. Crystal structures of human group-VIIA phospholipase A2 inhibited by organophosphorus nerve agents exhibit non-aged complexes. Biochem Pharmacol. 2009 Aug 15; 78(4):420-9.
-
Qaseem A, Snow V, Cross JT, Forciea MA, Hopkins R, Shekelle P, Adelman A, Mehr D, Schellhase K, Campos-Outcalt D, Santaguida P, Owens DK. Current pharmacologic treatment of dementia: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians. Ann Intern Med. 2008 Mar 04; 148(5):370-8.
-
Stefanacci RG. Current implications for the managed care of dementia. Am J Manag Care. 2007 Dec; 13 Suppl 8:S203-5; discussion S206-7.
-
Zhang MY, Hughes ZA, Kerns EH, Lin Q, Beyer CE. Development of a liquid chromatography/tandem mass spectrometry method for the quantitation of acetylcholine and related neurotransmitters in brain microdialysis samples. J Pharm Biomed Anal. 2007 Jun 28; 44(2):586-93.
-
Zarowitz BJ, Stefanacci R, Hollenack K, O'Shea T, Gruber J, Tangalos EG. The application of evidence-based principles of care in older persons (issue 5): Alzheimer's disease. J Am Med Dir Assoc. 2007 Mar; 8(3):183-93.
-
Lippa CF. An individualized approach to treatment for alzheimer's disease, pick's disease, and other dementias. Am J Alzheimers Dis Other Demen. 2006 Oct-Nov; 21(5):354-9.