"Cycloheximide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.
| Descriptor ID |
D003513
|
| MeSH Number(s) |
D03.383.621.808.240
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cycloheximide".
Below are MeSH descriptors whose meaning is more specific than "Cycloheximide".
This graph shows the total number of publications written about "Cycloheximide" by people in this website by year, and whether "Cycloheximide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 3 | 3 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Cycloheximide" by people in Profiles.
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Pucci B, Indelicato M, Paradisi V, Reali V, Pellegrini L, Aventaggiato M, Karpinich NO, Fini M, Russo MA, Farber JL, Tafani M. ERK-1 MAP kinase prevents TNF-induced apoptosis through bad phosphorylation and inhibition of Bax translocation in HeLa Cells. J Cell Biochem. 2009 Dec 01; 108(5):1166-74.
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Pucci B, Bertani F, Karpinich NO, Indelicato M, Russo MA, Farber JL, Tafani M. Detailing the role of Bax translocation, cytochrome c release, and perinuclear clustering of the mitochondria in the killing of HeLa cells by TNF. J Cell Physiol. 2008 Nov; 217(2):442-9.
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Tafani M, Cohn JA, Karpinich NO, Rothman RJ, Russo MA, Farber JL. Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha. J Biol Chem. 2002 Dec 20; 277(51):49569-76.
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Karpinich NO, Tafani M, Rothman RJ, Russo MA, Farber JL. The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. J Biol Chem. 2002 May 10; 277(19):16547-52.
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Kucich U, Rosenbloom JC, Abrams WR, Rosenbloom J. Transforming growth factor-beta stabilizes elastin mRNA by a pathway requiring active Smads, protein kinase C-delta, and p38. Am J Respir Cell Mol Biol. 2002 Feb; 26(2):183-8.
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Garver E, Cao QN, Aini M, Zhou F, Israel Y. Eliciting the low-activity aldehyde dehydrogenase Asian phenotype by an antisense mechanism results in an aversion to ethanol. J Exp Med. 2001 Sep 03; 194(5):571-80.
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White MK, Baireddy V, Strayer DS. Natural protection from apoptosis by surfactant protein A in type II pneumocytes. Exp Cell Res. 2001 Feb 15; 263(2):183-92.
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Kucich U, Rosenbloom JC, Shen G, Abrams WR, Hamilton AD, Sebti SM, Rosenbloom J. TGF-beta1 stimulation of fibronectin transcription in cultured human lung fibroblasts requires active geranylgeranyl transferase I, phosphatidylcholine-specific phospholipase C, protein kinase C-delta, and p38, but not erk1/erk2. Arch Biochem Biophys. 2000 Feb 15; 374(2):313-24.
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Chaqour B, Howard PS, Richards CF, Macarak EJ. Mechanical stretch induces platelet-activating factor receptor gene expression through the NF-kappaB transcription factor. J Mol Cell Cardiol. 1999 Jul; 31(7):1345-55.
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Darling TN, Yee C, Koh B, McGrath JA, Bauer JW, Uitto J, Hintner H, Yancey KB. Cycloheximide facilitates the identification of aberrant transcripts resulting from a novel splice-site mutation in COL17A1 in a patient with generalized atrophic benign epidermolysis bullosa. J Invest Dermatol. 1998 Feb; 110(2):165-9.