"Cyclosporins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.
| Descriptor ID |
D003524
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| MeSH Number(s) |
D04.345.566.235 D12.644.641.235
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclosporins".
Below are MeSH descriptors whose meaning is more specific than "Cyclosporins".
This graph shows the total number of publications written about "Cyclosporins" by people in this website by year, and whether "Cyclosporins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclosporins" by people in Profiles.
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Manara MC, Perdichizzi S, Serra M, Pierini R, Benini S, Hattinger CM, Astolfi A, Bagnati R, D'Incalci M, Picci P, Scotlandi K. The molecular mechanisms responsible for resistance to ET-743 (Trabectidin; Yondelis) in the Ewing's sarcoma cell line, TC-71. Int J Oncol. 2005 Dec; 27(6):1605-16.
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Kaiser BA, Lawless ST, Palmer JM, Dunn SP, Polinsky MS, Baluarte HJ. Safe conversion from cyclosporine to azathioprine with improved renal function in pediatric renal transplantation. Pediatr Nephrol. 1989 Oct; 3(4):401-5.
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McGregor RS, Zitelli BJ, Urbach AH, Malatack JJ, Gartner JC. Varicella in pediatric orthotopic liver transplant recipients. Pediatrics. 1989 Feb; 83(2):256-61.
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Bielory L, Holland C, Gascon P, Frohman L. Uveitis, cutaneous and neurosarcoid: treatment with low-dose cyclosporine A. Transplant Proc. 1988 Jun; 20(3 Suppl 4):144-8.
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Ledley GS, Sulica VI, Kao GF. Kaposi's sarcoma in a renal transplant patient receiving cyclosporine. Am J Med Sci. 1987 Sep; 294(3):211-3.
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Eisen HJ, Eisenberg SB, Saffitz JE, Bolman RM, Sobel BE, Bergmann SR. Noninvasive detection of rejection of transplanted hearts with indium-111-labeled lymphocytes. Circulation. 1987 Apr; 75(4):868-76.
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Gartner JC, Zitelli BJ, Malatack JJ, Shaw BW, Iwatsuki S, Starzl TE. Orthotopic liver transplantation in children: two-year experience with 47 patients. Pediatrics. 1984 Jul; 74(1):140-5.