Electron Transport Complex IV
"Electron Transport Complex IV" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multisubunit enzyme complex containing CYTOCHROME A GROUP; CYTOCHROME A3; two copper atoms; and 13 different protein subunits. It is the terminal oxidase complex of the RESPIRATORY CHAIN and collects electrons that are transferred from the reduced CYTOCHROME C GROUP and donates them to molecular OXYGEN, which is then reduced to water. The redox reaction is simultaneously coupled to the transport of PROTONS across the inner mitochondrial membrane.
Descriptor ID |
D003576
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MeSH Number(s) |
D05.500.562.374 D08.811.600.250.687 D08.811.682.285 D12.776.157.530.450.250.875.304 D12.776.543.277.687 D12.776.543.585.450.250.875.484
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Concept/Terms |
Electron Transport Complex IV- Electron Transport Complex IV
- Ferrocytochrome c Oxygen Oxidoreductase
- Cytochrome-c Oxidase (Complex IV)
- Cytochrome Oxidase
- Oxidase, Cytochrome
- Cytochrome-c Oxidase
- Cytochrome c Oxidase
- Oxidase, Cytochrome-c
Signal Peptide p25-Subunit IV Cytochrome Oxidase- Signal Peptide p25-Subunit IV Cytochrome Oxidase
- Signal Peptide p25 Subunit IV Cytochrome Oxidase
- Pre-CTOX p25
- p25 Presequence Peptide-Cytochrome Oxidase
- p25 Presequence Peptide Cytochrome Oxidase
Cytochrome aa3- Cytochrome aa3
- Heme aa3 Cytochrome Oxidase
- Cytochrome a,a3
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Below are MeSH descriptors whose meaning is more general than "Electron Transport Complex IV".
Below are MeSH descriptors whose meaning is more specific than "Electron Transport Complex IV".
This graph shows the total number of publications written about "Electron Transport Complex IV" by people in this website by year, and whether "Electron Transport Complex IV" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 1 | 2 |
2005 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2010 | 1 | 1 | 2 |
2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Electron Transport Complex IV" by people in Profiles.
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Whitaker-Menezes D, Martinez-Outschoorn UE, Flomenberg N, Birbe RC, Witkiewicz AK, Howell A, Pavlides S, Tsirigos A, Ertel A, Pestell RG, Broda P, Minetti C, Lisanti MP, Sotgia F. Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue. Cell Cycle. 2011 Dec 1; 10(23):4047-64.
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Mimaki M, Hatakeyama H, Komaki H, Yokoyama M, Arai H, Kirino Y, Suzuki T, Nishino I, Nonaka I, Goto Y. Reversible infantile respiratory chain deficiency: a clinical and molecular study. Ann Neurol. 2010 Dec; 68(6):845-54.
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Masuda I, Matsuzaki M, Kita K. Extensive frameshift at all AGG and CCC codons in the mitochondrial cytochrome c oxidase subunit 1 gene of Perkinsus marinus (Alveolata; Dinoflagellata). Nucleic Acids Res. 2010 Oct; 38(18):6186-94.
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Kamikawa R, Masuda I, Demura M, Oyama K, Yoshimatsu S, Kawachi M, Sako Y. Mitochondrial group II introns in the raphidophycean flagellate Chattonella spp. suggest a diatom-to-Chattonella lateral group II intron transfer. Protist. 2009 Aug; 160(3):364-75.
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Farrell SR, Thorpe C. Augmenter of liver regeneration: a flavin-dependent sulfhydryl oxidase with cytochrome c reductase activity. Biochemistry. 2005 Feb 8; 44(5):1532-41.
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Zhu S, Li M, Figueroa BE, Liu A, Stavrovskaya IG, Pasinelli P, Beal MF, Brown RH, Kristal BS, Ferrante RJ, Friedlander RM. Prophylactic creatine administration mediates neuroprotection in cerebral ischemia in mice. J Neurosci. 2004 Jun 30; 24(26):5909-12.
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Boopathi E, Lenka N, Prabu SK, Fang JK, Wilkinson F, Atchison M, Giallongo A, Avadhani NG. Regulation of murine cytochrome c oxidase Vb gene expression during myogenesis: YY-1 and heterogeneous nuclear ribonucleoprotein D-like protein (JKTBP1) reciprocally regulate transcription activity by physical interaction with the BERF-1/ZBP-89 factor. J Biol Chem. 2004 Aug 20; 279(34):35242-54.
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Okayasu T, Curtis MT, Farber JL. Structural alterations of the inner mitochondrial membrane in ischemic liver cell injury. Arch Biochem Biophys. 1985 Feb 1; 236(2):638-45.