"Dyneins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of multisubunit cytoskeletal motor proteins that use the energy of ATP hydrolysis, generated by a ring of AAA ATPASES in the dynein heavy chain, to power a variety of cellular functions. Dyneins fall into two major classes based upon structural and functional criteria.
Descriptor ID |
D004398
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MeSH Number(s) |
D08.811.277.040.013.500.063 D08.811.277.040.025.024.063 D08.811.277.040.025.193.249 D12.776.157.025.750.063 D12.776.220.600.200
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Concept/Terms |
Dyneins- Dyneins
- Adenosine Triphosphatase, Dynein
- Dynein Adenosine Triphosphatase
- Adenosinetriphosphatase, Dynein
- ATPase, Dynein
- Dynein ATPase
- Dynein
- Dynein Adenosinetriphosphatase
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Below are MeSH descriptors whose meaning is more general than "Dyneins".
Below are MeSH descriptors whose meaning is more specific than "Dyneins".
This graph shows the total number of publications written about "Dyneins" by people in this website by year, and whether "Dyneins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2007 | 1 | 0 | 1 |
2008 | 1 | 1 | 2 |
2009 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2017 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dyneins" by people in Profiles.
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Nunnari G, Sanfilippo C, Castrogiovanni P, Imbesi R, Li Volti G, Barbagallo I, Musumeci G, Di Rosa M. Network perturbation analysis in human bronchial epithelial cells following SARS-CoV2 infection. Exp Cell Res. 2020 10 15; 395(2):112204.
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Cristofani R, Crippa V, Rusmini P, Cicardi ME, Meroni M, Licata NV, Sala G, Giorgetti E, Grunseich C, Galbiati M, Piccolella M, Messi E, Ferrarese C, Carra S, Poletti A. Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases. Autophagy. 2017 Aug 03; 13(8):1280-1303.
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Varma D, Dawn A, Ghosh-Roy A, Weil SJ, Ori-McKenney KM, Zhao Y, Keen J, Vallee RB, Williams JC. Development and application of in vivo molecular traps reveals that dynein light chain occupancy differentially affects dynein-mediated processes. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3493-8.
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Lightcap CM, Kari G, Arias-Romero LE, Chernoff J, Rodeck U, Williams JC. Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development. PLoS One. 2009; 4(6):e6025.
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Ilieva HS, Yamanaka K, Malkmus S, Kakinohana O, Yaksh T, Marsala M, Cleveland DW. Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death. Proc Natl Acad Sci U S A. 2008 Aug 26; 105(34):12599-604.
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Lightcap CM, Sun S, Lear JD, Rodeck U, Polenova T, Williams JC. Biochemical and structural characterization of the Pak1-LC8 interaction. J Biol Chem. 2008 Oct 3; 283(40):27314-24.
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Tan GS, Preuss MA, Williams JC, Schnell MJ. The dynein light chain 8 binding motif of rabies virus phosphoprotein promotes efficient viral transcription. Proc Natl Acad Sci U S A. 2007 Apr 24; 104(17):7229-34.