Below are the most recent publications written about "Ectromelia virus" by people in Profiles.
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Montoya B, Knudson CJ, Melo-Silva CR, Tang L, Kafle S, Sigal LJ. Resistance To Poxvirus Lethality Does Not Require the Necroptosis Proteins RIPK3 or MLKL. J Virol. 2023 02 28; 97(2):e0194522.
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Melo-Silva CR, Roman MI, Knudson CJ, Tang L, Xu RH, Tassetto M, Dolan P, Andino R, Sigal LJ. Interferon partly dictates a divergent transcriptional response in poxvirus-infected and bystander inflammatory monocytes. Cell Rep. 2022 11 22; 41(8):111676.
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Knudson CJ, F?rez M, Alves-Peixoto P, Erkes DA, Melo-Silva CR, Tang L, Snyder CM, Sigal LJ. Mechanisms of Antiviral Cytotoxic CD4 T Cell Differentiation. J Virol. 2021 09 09; 95(19):e0056621.
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Melo-Silva CR, Alves-Peixoto P, Heath N, Tang L, Montoya B, Knudson CJ, Stotesbury C, Ferez M, Wong E, Sigal LJ. Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells. PLoS Pathog. 2021 05; 17(5):e1009593.
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Forsyth KS, Roy NH, Peauroi E, DeHaven BC, Wold ED, Hersperger AR, Burkhardt JK, Eisenlohr LC. Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4+?T cells post peptide loading. PLoS Pathog. 2020 08; 16(8):e1008685.
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Stotesbury C, Wong EB, Tang L, Montoya B, Knudson CJ, Melo-Silva CR, Sigal LJ. Defective early innate immune response to ectromelia virus in the draining lymph nodes of aged mice due to impaired dendritic cell accumulation. Aging Cell. 2020 07; 19(7):e13170.
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Stotesbury C, Alves-Peixoto P, Montoya B, Ferez M, Nair S, Snyder CM, Zhang S, Knudson CJ, Sigal LJ. a2?1 Integrin Is Required for Optimal NK Cell Proliferation during Viral Infection but Not for Acquisition of Effector Functions or NK Cell-Mediated Virus Control. J Immunol. 2020 03 15; 204(6):1582-1591.
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Wong EB, Montoya B, Ferez M, Stotesbury C, Sigal LJ. Resistance to ectromelia virus infection requires cGAS in bone marrow-derived cells which can be bypassed with cGAMP therapy. PLoS Pathog. 2019 12; 15(12):e1008239.
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Wong E, Xu RH, Rubio D, Lev A, Stotesbury C, Fang M, Sigal LJ. Migratory Dendritic Cells, Group 1 Innate Lymphoid Cells, and Inflammatory Monocytes Collaborate to Recruit NK Cells to the Virus-Infected Lymph Node. Cell Rep. 2018 07 03; 24(1):142-154.
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Frey TR, Forsyth KS, Sheehan MM, De Haven BC, Pevarnik JG, Hand ES, Pizzorno MC, Eisenlohr LC, Hersperger AR. Ectromelia virus lacking the E3L ortholog is replication-defective and nonpathogenic but does induce protective immunity in a mouse strain susceptible to lethal mousepox. Virology. 2018 05; 518:335-348.