Epitopes, T-Lymphocyte

"Epitopes, T-Lymphocyte" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Antigenic determinants recognized and bound by the T-cell receptor. Epitopes recognized by the T-cell receptor are often located in the inner, unexposed side of the antigen, and become accessible to the T-cell receptors after proteolytic processing of the antigen.

Descriptor ID	D018984
MeSH Number(s)	D23.050.550.402
Concept/Terms	Epitopes, T-Lymphocyte Epitopes, T-Lymphocyte Epitopes, T Lymphocyte T-Cell Epitopes Epitopes, T-Cell T Cell Epitopes T-Lymphocyte Epitopes T Lymphocyte Epitopes T-Cell Epitope Epitope, T-Cell T Cell Epitope T-Lymphocyte Epitope Epitope, T-Lymphocyte T Lymphocyte Epitope

Below are MeSH descriptors whose meaning is more general than "Epitopes, T-Lymphocyte".

Chemicals and Drugs [D]
Biological Factors [D23]
Antigens [D23.050]
Epitopes [D23.050.550]
Epitopes, T-Lymphocyte [D23.050.550.402]

Below are MeSH descriptors whose meaning is related to "Epitopes, T-Lymphocyte".

Below are MeSH descriptors whose meaning is more specific than "Epitopes, T-Lymphocyte".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Epitopes, T-Lymphocyte" by people in this website by year, and whether "Epitopes, T-Lymphocyte" was a major or minor topic of these publications.

Bar chart showing 46 publications over 22 distinct years, with a maximum of 5 publications in 2006 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	2	0	2
1999	1	0	1
2000	1	0	1
2001	1	1	2
2002	2	0	2
2003	1	3	4
2004	0	1	1
2005	2	0	2
2006	4	1	5
2007	0	1	1
2008	1	2	3
2010	1	2	3
2011	1	1	2
2012	1	0	1
2013	0	1	1
2014	0	5	5
2017	0	1	1
2020	1	2	3
2021	1	0	1
2022	0	1	1
2023	0	3	3
2026	1	0	1

Below are the most recent publications written about "Epitopes, T-Lymphocyte" by people in Profiles.

Grifoni A, Sidney J, Weiskopf D, Scheuermann RH, Sette A. A Roadmap Towards the Identification and Validation of Conserved T Cell Epitope Regions in Viral Pathogen Families with Pandemic Potential. Curr Pharm Biotechnol. 2026; 27(3):277-289.

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Hogan MJ, Maheshwari N, Begg BE, Nicastri A, Hedgepeth EJ, Muramatsu H, Pardi N, Miller MA, Reilly SP, Brossay L, Lynch KW, Ternette N, Eisenlohr LC. Cryptic MHC-E epitope from influenza elicits a potent cytolytic T cell response. Nat Immunol. 2023 11; 24(11):1933-1946.

View in: PubMed
Pan Y, Phillips JW, Zhang BD, Noguchi M, Kutschera E, McLaughlin J, Nesterenko PA, Mao Z, Bangayan NJ, Wang R, Tran W, Yang HT, Wang Y, Xu Y, Obusan MB, Cheng D, Lee AH, Kadash-Edmondson KE, Champhekar A, Puig-Saus C, Ribas A, Prins RM, Seet CS, Crooks GM, Witte ON, Xing Y. IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing. Proc Natl Acad Sci U S A. 2023 05 23; 120(21):e2221116120.

View in: PubMed
Qin J, Jeon JH, Xu J, Langston LK, Marasini R, Mou S, Montoya B, Melo-Silva CR, Jeon HJ, Zhu T, Sigal LJ, Xu R, Zhu H. Design and preclinical evaluation of a universal SARS-CoV-2 mRNA vaccine. Front Immunol. 2023; 14:1126392.

View in: PubMed
Palatnik-de-Sousa I, Wallace ZS, Cavalcante SC, Ribeiro MPF, Silva JABM, Cavalcante RC, Scheuermann RH, Palatnik-de-Sousa CB. A novel vaccine based on SARS-CoV-2 CD4+ and CD8+ T cell conserved epitopes from variants Alpha to Omicron. Sci Rep. 2022 10 06; 12(1):16731.

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Shehata MM, Mahmoud SH, Tarek M, Al-Karmalawy AA, Mahmoud A, Mostafa A, M Elhefnawi M, Ali MA. In Silico and In Vivo Evaluation of SARS-CoV-2 Predicted Epitopes-Based Candidate Vaccine. Molecules. 2021 Oct 13; 26(20).

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Parvizpour S, Pourseif MM, Razmara J, Rafi MA, Omidi Y. Epitope-based vaccine design: a comprehensive overview of bioinformatics approaches. Drug Discov Today. 2020 06; 25(6):1034-1042.

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Grifoni A, Sidney J, Zhang Y, Scheuermann RH, Peters B, Sette A. A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2. Cell Host Microbe. 2020 04 08; 27(4):671-680.e2.

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Cho KJ, Ishido S, Eisenlohr LC, Roche PA. Activation of Dendritic Cells Alters the Mechanism of MHC Class II Antigen Presentation to CD4 T Cells. J Immunol. 2020 03 15; 204(6):1621-1629.

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Erkes DA, Wilski NA, Snyder CM. Intratumoral infection by CMV may change the tumor environment by directly interacting with tumor-associated macrophages to promote cancer immunity. Hum Vaccin Immunother. 2017 08 03; 13(8):1778-1785.

View in: PubMed

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