Necrosis

"Necrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.

Descriptor ID	D009336
MeSH Number(s)	C23.550.717 G04.146.638
Concept/Terms	Necrosis Necrosis Necroses

Below are MeSH descriptors whose meaning is more general than "Necrosis".

Diseases [C]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Necrosis [C23.550.717]
Biological Sciences [G]
Cell Physiological Phenomena [G04]
Cell Death [G04.146]
Necrosis [G04.146.638]

Below are MeSH descriptors whose meaning is related to "Necrosis".

Below are MeSH descriptors whose meaning is more specific than "Necrosis".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Necrosis" by people in this website by year, and whether "Necrosis" was a major or minor topic of these publications.

Bar chart showing 148 publications over 30 distinct years, with a maximum of 15 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	3	3
1997	0	5	5
1998	0	5	5
1999	0	2	2
2000	0	3	3
2001	0	2	2
2002	0	6	6
2003	0	2	2
2004	0	5	5
2005	0	5	5
2006	0	5	5
2007	1	14	15
2008	0	9	9
2009	0	6	6
2010	0	3	3
2011	1	6	7
2012	1	2	3
2013	1	7	8
2014	0	1	1
2015	1	3	4
2016	0	3	3
2017	1	3	4
2018	2	9	11
2019	0	5	5
2020	0	10	10
2021	0	6	6
2022	0	3	3
2023	0	2	2
2024	3	1	4
2025	0	1	1

Below are the most recent publications written about "Necrosis" by people in Profiles.

Yadav VK, Sharma S, Maurya S, Singh RK, Saini J, Jain P, Patir R, Ahlawat S, Das S, Vaishya S, Agarwal S, Singh A, Gupta RK. Presence of Fragmented Intratumoral Thrombosed Microvasculature in the Necrotic and Peri-Necrotic Regions on SWI Differentiates IDH Wild-Type Glioblastoma From IDH Mutant Grade 4 Astrocytoma. J Magn Reson Imaging. 2025 Jul; 62(1):258-270.

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Arango SD, Flynn JC, Zeitlin JH, Weir TB, Miller AJ. Xylazine-Associated Necrotic Upper-Extremity Wounds: A Single Hospital System's Experience with 82 Patients and 125 Wounds. J Bone Joint Surg Am. 2025 Feb 05; 107(3):279-286.

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Loesch AJ, Jin A, Huang S, Motaparthi K, Lee JB, Hsu S. Methotrexate-Induced Epidermal Necrosis. Skinmed. 2024; 22(5):387-389.

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Arango SD, Weir TB, Miller AJ, Osterman MN. Skin necrosis following digital wart intralesional injection of cantharidin. Dermatol Online J. 2024 Oct 15; 30(5).

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Jones VM, Nelson JA, Sevilimedu V, Le T, Allen RJ, Mehrara BJ, Barrio AV, Capko DM, Heerdt AS, Tadros AB, Gemignani ML, Morrow M, Sacchini V, Moo TA. Impact of Mastectomy Flap Necrosis on Patient-Reported Quality-of-Life Measures After Nipple-Sparing Mastectomy: A Preliminary Analysis. Ann Surg Oncol. 2024 Oct; 31(10):6795-6803.

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Moo TA, Nelson JA, Sevilimedu V, Charyn J, Le TV, Allen RJ, Mehrara BJ, Barrio AV, Capko DM, Pilewskie M, Heerdt AS, Tadros AB, Gemignani ML, Morrow M, Sacchini V. Strategies to avoid mastectomy skin-flap necrosis during nipple-sparing mastectomy. Br J Surg. 2023 06 12; 110(7):831-838.

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Alwelaie Y, Howaidi A, Tashkandi M, Almotairi A, Saied H, Muzzaffar M, Alghamdi D. Revisiting the cytomorphological features of poorly differentiated thyroid carcinoma: a comparative analysis with indeterminate thyroid fine-needle aspiration samples. J Am Soc Cytopathol. 2023 Sep-Oct; 12(5):331-340.

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Blomain E, Berta S, Hug N, Giao D, Meola A, Binkley M, Hui C, Churilla T, Shahsavari N, Desai K, Chang S, Soltys S, Pollom E. Radiotherapy for Brain Metastases from Thyroid Cancer: An Institutional and National Retrospective Cohort Study. Thyroid. 2022 07; 32(7):781-788.

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Slijepcevic AA, Young G, Shinn J, Cannady SB, Hanasono M, Old M, Grewal JS, Ghanem T, Ducic Y, Curry JM, Wax MK. Success and Outcomes Following a Second Salvage Attempt for Free Flap Compromise in Patients Undergoing Head and Neck Reconstruction. JAMA Otolaryngol Head Neck Surg. 2022 06 01; 148(6):555-560.

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Liu X, Guo L, Xie FY, Hu WH, Chen MY, He QM, Xu ZM, Zhang CQ, Peng YL, Tang LL, Mao YP, Sun R, Li JB, Argiris A, Hui EP, Sun Y, Ma J. Adjuvant Apatinib in Nasopharyngeal Carcinoma With Residual Epstein-Barr Virus DNA After Radiation Therapy: A Biomarker-Driven, Phase 2 Trial. Int J Radiat Oncol Biol Phys. 2022 08 01; 113(5):1063-1071.

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