Muscle Weakness

"Muscle Weakness" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251)

Descriptor ID	D018908
MeSH Number(s)	C05.651.515 C10.597.613.593 C23.550.695 C23.888.592.608.593
Concept/Terms	Muscle Weakness Muscle Weakness Muscle Weaknesses Weakness, Muscle Weaknesses, Muscle Muscular Weakness Muscular Weaknesses Weakness, Muscular Weaknesses, Muscular

Below are MeSH descriptors whose meaning is more general than "Muscle Weakness".

Diseases [C]
Musculoskeletal Diseases [C05]
Muscular Diseases [C05.651]
Muscle Weakness [C05.651.515]
Nervous System Diseases [C10]
Neurologic Manifestations [C10.597]
Neuromuscular Manifestations [C10.597.613]
Muscle Weakness [C10.597.613.593]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Muscle Weakness [C23.550.695]
Signs and Symptoms [C23.888]
Neurologic Manifestations [C23.888.592]
Neuromuscular Manifestations [C23.888.592.608]
Muscle Weakness [C23.888.592.608.593]

Below are MeSH descriptors whose meaning is related to "Muscle Weakness".

Below are MeSH descriptors whose meaning is more specific than "Muscle Weakness".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Muscle Weakness" by people in this website by year, and whether "Muscle Weakness" was a major or minor topic of these publications.

Bar chart showing 71 publications over 24 distinct years, with a maximum of 8 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1999	1	0	1
2000	2	0	2
2002	0	1	1
2003	0	1	1
2004	0	3	3
2005	4	2	6
2006	0	2	2
2007	1	1	2
2008	4	4	8
2009	1	2	3
2010	0	1	1
2011	2	0	2
2012	4	1	5
2013	1	4	5
2014	1	2	3
2015	3	2	5
2016	0	3	3
2017	2	1	3
2018	2	0	2
2019	2	2	4
2020	2	2	4
2022	1	2	3
2025	1	0	1

Below are the most recent publications written about "Muscle Weakness" by people in Profiles.

van Duijnhoven E, Waterval NF, Koopman FS, Esquenazi A, Nollet F, Brehm MA. Ankle-foot orthoses for improving walking in adults with calf muscle weakness due to neuromuscular disorders. Cochrane Database Syst Rev. 2025 01 16; 1:CD014871.

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Gruber D, Lloyd-Puryear M, Armstrong N, Scavina M, Tavakoli NP, Brower AM, Caggana M, Chung WK. Newborn screening for Duchenne muscular dystrophy-early detection and diagnostic algorithm for female carriers of Duchenne muscular dystrophy. Am J Med Genet C Semin Med Genet. 2022 06; 190(2):197-205.

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Kirupaharan P, Kramer D, Gandler A, Kenyon L, Summer R. 68-year old man with progressive weakness and ventilator dependent respiratory failure: a case report of sporadic late onset nemaline myopathy. BMC Pulm Med. 2022 Mar 19; 22(1):97.

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Pugliese JM, Coyle PC, Knox PJ, Sions JM, Patterson CG, Pohlig RT, Simon CB, Weiner DK, George SZ, Piva S, Hicks GE. The Manual Therapy and Strengthening for the Hip (MASH) Trial: Protocol for a Multisite Randomized Trial of a Subgroup of Older Adults With Chronic Back and Hip Pain. Phys Ther. 2022 01 01; 102(1).

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Murphy OC, Messacar K, Benson L, Bove R, Carpenter JL, Crawford T, Dean J, DeBiasi R, Desai J, Elrick MJ, Farias-Moeller R, Gombolay GY, Greenberg B, Harmelink M, Hong S, Hopkins SE, Oleszek J, Otten C, Sadowsky CL, Schreiner TL, Thakur KT, Van Haren K, Carballo CM, Chong PF, Fall A, Gowda VK, Helfferich J, Kira R, Lim M, Lopez EL, Wells EM, Yeh EA, Pardo CA. Acute flaccid myelitis: cause, diagnosis, and management. Lancet. 2021 01 23; 397(10271):334-346.

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O'Mathuna D, Berghella V, Bellussi F, Kumar N, Haas DM. Cochrane Review Summaries-October 2020. Obstet Gynecol. 2020 10; 136(4):844-846.

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Mendoza-Ferreira N, Karakaya M, Cengiz N, Beijer D, Brigatti KW, Gonzaga-Jauregui C, Fuhrmann N, H?lker I, Thelen MP, Zetzsche S, Rombo R, Puffenberger EG, De Jonghe P, Deconinck T, Zuchner S, Strauss KA, Carson V, Schrank B, Wunderlich G, Baets J, Wirth B. De Novo and Inherited Variants in GBF1 are Associated with Axonal Neuropathy Caused by Golgi Fragmentation. Am J Hum Genet. 2020 10 01; 107(4):763-777.

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Dillingham TR, Annaswamy TM, Plastaras CT. Evaluation of persons with suspected lumbosacral and cervical radiculopathy: Electrodiagnostic assessment and implications for treatment and outcomes (Part I). Muscle Nerve. 2020 10; 62(4):462-473.

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Zimmers TA, Koniaris LG. Modelling survival. Elife. 2019 12 10; 8.

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Debattisti V, Horn A, Singh R, Seifert EL, Hogarth MW, Mazala DA, Huang KT, Horvath R, Jaiswal JK, Hajn?czky G. Dysregulation of Mitochondrial Ca2+ Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1. Cell Rep. 2019 10 29; 29(5):1274-1286.e6.

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