"Pancreatic Polypeptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.
| Descriptor ID |
D010191
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| MeSH Number(s) |
D06.472.699.587.700 D12.644.400.600 D12.644.548.586.700 D12.776.631.650.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pancreatic Polypeptide".
Below are MeSH descriptors whose meaning is more specific than "Pancreatic Polypeptide".
This graph shows the total number of publications written about "Pancreatic Polypeptide" by people in this website by year, and whether "Pancreatic Polypeptide" was a major or minor topic of these publications.
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Below are the most recent publications written about "Pancreatic Polypeptide" by people in Profiles.
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Lu LJ, Anderson KE, Gomez G, Nealon WH. Decreased plasma levels of cholecystokinin in healthy males after chronic ingestion of a heat-treated soya product. Cancer Lett. 1995 Apr 14; 90(2):149-55.
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Beauchamp RD, MacLellan DG, Upp JR, Nealon WH, Townsend CM, Thompson JC. The role of endogenous prostaglandins in hormone-stimulated pancreatic exocrine secretion. Gastroenterology. 1992 Jan; 102(1):272-9.
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Beauchamp RD, Gomez G, Nealon WH, Townsend CM, Greeley GH, Thompson JC. Proglumide inhibits cholecystokinin and meal-stimulated pancreatic secretion and release of pancreatic polypeptide. Surgery. 1990 Sep; 108(3):553-8.
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Bastidas JA, Couse NF, Yeo CJ, Schmieg RE, Andersen DK, Gingerich RL, Zinner MJ. The effect of pancreatic polypeptide infusion on glucose tolerance and insulin response in longitudinally studied pancreatitis-induced diabetes. Surgery. 1990 Jun; 107(6):661-8.
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Bastidas JA, Yeo CJ, Couse NF, Schmieg RE, Andersen DK, Gingerich RL, Zinner MJ. Ultrastructure and endocrine function in acute and chronic pancreatitis: results of pancreatic polypeptide replacement. Curr Surg. 1989 Sep-Oct; 46(5):390-2.
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Nealon WH, Townsend CM, Thompson JC. The time course of beta cell dysfunction in chronic ethanol-induced pancreatitis: a prospective analysis. Surgery. 1988 Dec; 104(6):1074-9.
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Nealon WH, Townsend CM, Thompson JC. Operative drainage of the pancreatic duct delays functional impairment in patients with chronic pancreatitis. A prospective analysis. Ann Surg. 1988 Sep; 208(3):321-9.
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Nealon WH, Beauchamp RD, Townsend CM, Boyd G, Shabot M, Thompson JC. Diagnostic role of gastrointestinal hormones in patients with chronic pancreatitis. Ann Surg. 1986 Oct; 204(4):430-7.