"Papaverine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
| Descriptor ID |
D010208
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| MeSH Number(s) |
D03.132.098.666 D03.132.577.750 D03.633.100.531.085.666
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Papaverine".
Below are MeSH descriptors whose meaning is more specific than "Papaverine".
This graph shows the total number of publications written about "Papaverine" by people in this website by year, and whether "Papaverine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 2 | 0 | 2 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Papaverine" by people in Profiles.
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Keller E, Wolf M, Martin M, Yonekawa Y. Estimation of cerebral oxygenation and hemodynamics in cerebral vasospasm using indocyaningreen dye dilution and near infrared spectroscopy: a case report. J Neurosurg Anesthesiol. 2001 Jan; 13(1):43-8.
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Rosenwasser RH, Armonda RA, Thomas JE, Benitez RP, Gannon PM, Harrop J. Therapeutic modalities for the management of cerebral vasospasm: timing of endovascular options. Neurosurgery. 1999 May; 44(5):975-9; discussion 979-80.
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Fandino J, Kaku Y, Schuknecht B, Valavanis A, Yonekawa Y. Improvement of cerebral oxygenation patterns and metabolic validation of superselective intraarterial infusion of papaverine for the treatment of cerebral vasospasm. J Neurosurg. 1998 Jul; 89(1):93-100.
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Elliott JP, Newell DW, Lam DJ, Eskridge JM, Douville CM, Le Roux PD, Lewis DH, Mayberg MR, Grady MS, Winn HR. Comparison of balloon angioplasty and papaverine infusion for the treatment of vasospasm following aneurysmal subarachnoid hemorrhage. J Neurosurg. 1998 Feb; 88(2):277-84.
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Pozza D, Ossanna P, Cicchinelli C, Pozza M, Rizzo GL, Marchionni L. [Intra-cavernous injections of vasoactive drugs. A 10-year experience at an andrologic center]. Minerva Urol Nefrol. 1996 Sep; 48(3):163-7.
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Chancellor MB, Rivas DA, Panzer DE, Freedman MK, Staas WE. Prospective comparison of topical minoxidil to vacuum constriction device and intracorporeal papaverine injection in treatment of erectile dysfunction due to spinal cord injury. Urology. 1994 Mar; 43(3):365-9.