"Pentobarbital" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
| Descriptor ID |
D010424
|
| MeSH Number(s) |
D03.383.742.698.253.593
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pentobarbital".
Below are MeSH descriptors whose meaning is more specific than "Pentobarbital".
This graph shows the total number of publications written about "Pentobarbital" by people in this website by year, and whether "Pentobarbital" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pentobarbital" by people in Profiles.
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Arbour RB, Dissin J. Predictive value of the bispectral index for burst suppression on diagnostic electroencephalogram during drug-induced coma. J Neurosci Nurs. 2015 Apr; 47(2):113-22.
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Riviello JJ, Claassen J, LaRoche SM, Sperling MR, Alldredge B, Bleck TP, Glauser T, Shutter L, Treiman DM, Vespa PM, Bell R, Brophy GM. Treatment of status epilepticus: an international survey of experts. Neurocrit Care. 2013 Apr; 18(2):193-200.
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Weissenburger J, Nesterenko VV, Antzelevitch C. Transmural heterogeneity of ventricular repolarization under baseline and long QT conditions in the canine heart in vivo: torsades de pointes develops with halothane but not pentobarbital anesthesia. J Cardiovasc Electrophysiol. 2000 Mar; 11(3):290-304.
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Shimizu W, McMahon B, Antzelevitch C. Sodium pentobarbital reduces transmural dispersion of repolarization and prevents torsades de Pointes in models of acquired and congenital long QT syndrome. J Cardiovasc Electrophysiol. 1999 Feb; 10(2):154-64.
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Jasani MS, Salzman SK, Tice LL, Ginn A, Nadkarni VM. Anesthetic regimen effects on a pediatric porcine model of asphyxial arrest. Resuscitation. 1997 Aug; 35(1):69-75.
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L? AD, Israel Y. A simple technique for quantifying intoxication-induced by low doses of ethanol. Pharmacol Biochem Behav. 1994 May; 48(1):229-34.
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Winer JW, Rosenwasser RH, Jimenez F. Electroencephalographic activity and serum and cerebrospinal fluid pentobarbital levels in determining the therapeutic end point during barbiturate coma. Neurosurgery. 1991 Nov; 29(5):739-41; discussion 741-2.
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Geller EB, Durlofsky L, Cowan A, Harakal C, Adler MW. The effect of pentobarbital on the antinociceptive action of morphine in morphine-tolerant and non-tolerant rats. Life Sci. 1979 Jul 09; 25(2):139-45.
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Poklis A, Hameli AZ. Two unusual barbiturate deaths. Arch Toxicol. 1975 Sep 05; 34(1):77-80.
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Israel Y, Carmichael FJ, Macdonald JA. Effects of ethanol on electrolyte metabolism and neurotransmitter release in the CNS. Adv Exp Med Biol. 1975; 59:55-64.