"Dihydrotestosterone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.
| Descriptor ID |
D013196
|
| MeSH Number(s) |
D04.210.500.054.040.248 D06.472.334.851.968.964
|
| Concept/Terms |
Dihydrotestosterone- Dihydrotestosterone
- 5 alpha-Dihydrotestosterone
- 5 alpha Dihydrotestosterone
- Androstanolone
- 5-alpha Dihydrotestosterone
- Dihydrotestosterone, 5-alpha
- Stanolone
- 5-alpha-DHT
- 5 alpha DHT
- 17beta-Hydroxy-5alpha-Androstan-3-One
- 17beta Hydroxy 5alpha Androstan 3 One
|
Below are MeSH descriptors whose meaning is more general than "Dihydrotestosterone".
Below are MeSH descriptors whose meaning is more specific than "Dihydrotestosterone".
This graph shows the total number of publications written about "Dihydrotestosterone" by people in this website by year, and whether "Dihydrotestosterone" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dihydrotestosterone" by people in Profiles.
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Lisberg A, Liu Y, Merry DE. Blocking the dimerization of polyglutamine-expanded androgen receptor protects cells from DHT-induced toxicity by increasing AR turnover. J Biol Chem. 2024 05; 300(5):107246.
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Casimiro MC, Di Sante G, Ju X, Li Z, Chen K, Crosariol M, Yaman I, Gormley M, Meng H, Lisanti MP, Pestell RG. Cyclin D1 Promotes Androgen-Dependent DNA Damage Repair in Prostate Cancer Cells. Cancer Res. 2016 Jan 15; 76(2):329-38.
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Barthold JS, Wang Y, Robbins A, Pike J, McDowell E, Johnson KJ, McCahan SM. Transcriptome analysis of the dihydrotestosterone-exposed fetal rat gubernaculum identifies common androgen and insulin-like 3 targets. Biol Reprod. 2013 Dec; 89(6):143.
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Orr CR, Montie HL, Liu Y, Bolzoni E, Jenkins SC, Wilson EM, Joseph JD, McDonnell DP, Merry DE. An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy. J Biol Chem. 2010 Nov 12; 285(46):35567-77.
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van der Deen M, Akech J, Wang T, FitzGerald TJ, Altieri DC, Languino LR, Lian JB, van Wijnen AJ, Stein JL, Stein GS. The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells. J Cell Biochem. 2010 Mar 01; 109(4):828-37.
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Wu K, Katiyar S, Witkiewicz A, Li A, McCue P, Song LN, Tian L, Jin M, Pestell RG. The cell fate determination factor dachshund inhibits androgen receptor signaling and prostate cancer cellular growth. Cancer Res. 2009 Apr 15; 69(8):3347-55.
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Asbell SO, Raimane KC, Montesano AT, Zeitzer KL, Asbell MD, Vijayakumar S. Prostate-specific antigen and androgens in African-American and white normal subjects and prostate cancer patients. J Natl Med Assoc. 2000 Sep; 92(9):445-9.
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Botero-Ruiz W, Laufer N, DeCherney AH, Polan ML, Haseltine FP, Behrman HR. The relationship between follicular fluid steroid concentration and successful fertilization of human oocytes in vitro. Fertil Steril. 1984 Jun; 41(6):820-6.