Receptors, Androgen

"Receptors, Androgen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins, generally found in the CYTOPLASM, that specifically bind ANDROGENS and mediate their cellular actions. The complex of the androgen and receptor migrates to the CELL NUCLEUS where it induces transcription of specific segments of DNA.

Descriptor ID	D011944
MeSH Number(s)	D12.776.826.750.150
Concept/Terms	Receptors, Androgen Receptors, Androgen Androgen Receptor Receptor, Androgen Androgen Receptors Dihydrotestosterone Receptors Testosterone Receptor Receptors, Androgens Androgens Receptors Receptors, Dihydrotestosterone Receptors, Stanolone Stanolone Receptors Stanolone Receptor Receptor, Stanolone 5 alpha-Dihydrotestosterone Receptor 5 alpha Dihydrotestosterone Receptor Receptor, 5 alpha-Dihydrotestosterone alpha-Dihydrotestosterone Receptor, 5 Receptor, Testosterone

Below are MeSH descriptors whose meaning is more general than "Receptors, Androgen".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Receptors, Cytoplasmic and Nuclear [D12.776.826]
Receptors, Steroid [D12.776.826.750]
Receptors, Androgen [D12.776.826.750.150]

Below are MeSH descriptors whose meaning is related to "Receptors, Androgen".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Androgen".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Androgen" by people in this website by year, and whether "Receptors, Androgen" was a major or minor topic of these publications.

Bar chart showing 106 publications over 29 distinct years, with a maximum of 13 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	1	0	1
1998	4	3	7
1999	1	0	1
2000	1	1	2
2001	2	0	2
2002	3	2	5
2003	1	0	1
2004	1	1	2
2006	1	1	2
2007	1	0	1
2008	2	0	2
2009	4	0	4
2010	1	1	2
2011	4	0	4
2012	4	3	7
2013	3	5	8
2014	2	2	4
2015	10	3	13
2016	2	0	2
2017	3	0	3
2018	2	1	3
2019	4	2	6
2020	0	1	1
2021	2	2	4
2022	0	5	5
2023	0	5	5
2024	5	1	6
2025	2	0	2

Below are the most recent publications written about "Receptors, Androgen" by people in Profiles.

Chahdi A, Jorgez C, Rosenfeld JA, Neetu N, Seth A. Androgen receptor ubiquitination links KCTD13 to genitourinary tract defects. FASEB J. 2025 Feb 28; 39(4):e70406.

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Jorgez CJ, Chahdi A, Flores H, O'Neill M, Seth A. Role of Kctd13 in modulating AR and SOX9 expression in different penile cell populations. Andrology. 2025 07; 13(5):1201-1212.

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Karliner J, Liu Y, Merry DE. Mutant androgen receptor induces neurite loss and senescence independently of ARE binding in a neuronal model of SBMA. Proc Natl Acad Sci U S A. 2024 07 16; 121(29):e2321408121.

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Karan D, Dubey S, Gunewardena S, Iczkowski KA, Singh M, Liu P, Poletti A, Choo YM, Chen HZ, Hamann MT. Manzamine A reduces androgen receptor transcription and synthesis by blocking E2F8-DNA interactions and effectively inhibits prostate tumor growth in mice. Mol Oncol. 2024 08; 18(8):1966-1979.

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Lisberg A, Liu Y, Merry DE. Blocking the dimerization of polyglutamine-expanded androgen receptor protects cells from DHT-induced toxicity by increasing AR turnover. J Biol Chem. 2024 05; 300(5):107246.

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McKay RR, Morgans AK, Shore ND, Dunshee C, Devgan G, Agarwal N. First-line combination treatment with PARP and androgen receptor-signaling inhibitors in HRR-deficient mCRPC: Applying clinical study findings to clinical practice in the United States. Cancer Treat Rev. 2024 May; 126:102726.

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Maranto C, Sabharwal L, Udhane V, Pitzen SP, McCluskey B, Qi S, O'Connor C, Devi S, Johnson S, Jacobsohn K, Banerjee A, Iczkowski KA, Wang L, Dehm SM, Nevalainen MT. Stat5 induces androgen receptor (AR) gene transcription in prostate cancer and offers a druggable pathway to target AR signaling. Sci Adv. 2024 03; 10(9):eadi2742.

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Chahdi A, Jorgez C, Seth A. Regulation of androgen receptor stability by the ?1 Pix/STUB1 complex. FASEB J. 2024 02; 38(2):e23408.

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Santasusagna S, Zhu S, Jawalagatti V, Carceles-Cordon M, Ertel A, Garcia-Longarte S, Song WM, Fujiwara N, Li P, Mendizabal I, Petrylak DP, Kelly WK, Reddy EP, Wang L, Schiewer MJ, Lujambio A, Karnes J, Knudsen KE, Cordon-Cardo C, Dong H, Huang H, Carracedo A, Hoshida Y, Rodriguez-Bravo V, Domingo-Domenech J. Master Transcription Factor Reprogramming Unleashes Selective Translation Promoting Castration Resistance and Immune Evasion in Lethal Prostate Cancer. Cancer Discov. 2023 12 12; 13(12):2584-2609.

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Agarwal N, Azad AA, Carles J, Fay AP, Matsubara N, Heinrich D, Szczylik C, De Giorgi U, Young Joung J, Fong PCC, Voog E, Jones RJ, Shore ND, Dunshee C, Zsch?bitz S, Oldenburg J, Lin X, Healy CG, Di Santo N, Zohren F, Fizazi K. Talazoparib plus enzalutamide in men with first-line metastatic castration-resistant prostate cancer (TALAPRO-2): a randomised, placebo-controlled, phase 3 trial. Lancet. 2023 07 22; 402(10398):291-303.

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