"Strychnine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid found in the seeds of STRYCHNOS NUX-VOMICA. It is a competitive antagonist at glycine receptors and thus a convulsant. It has been used as an analeptic, in the treatment of nonketotic hyperglycinemia and sleep apnea, and as a rat poison.
| Descriptor ID |
D013331
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| MeSH Number(s) |
D03.132.436.681.722 D03.633.100.473.402.681.722
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Strychnine".
Below are MeSH descriptors whose meaning is more specific than "Strychnine".
This graph shows the total number of publications written about "Strychnine" by people in this website by year, and whether "Strychnine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Strychnine" by people in Profiles.
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Monnerie H, Hsu FC, Coulter DA, Le Roux PD. Role of the NR2A/2B subunits of the N-methyl-D-aspartate receptor in glutamate-induced glutamic acid decarboxylase alteration in cortical GABAergic neurons in vitro. Neuroscience. 2010 Dec 29; 171(4):1075-90.
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Mondadori C, Gentsch C, Hengerer B, Ducret T, Borkowski J, Racine A, Lederer R, Haeusler A. Pretreatment with aldosterone or corticosterone blocks the memory-enhancing effects of nimodipine, captopril, CGP 37,849, and strychnine in mice. Psychopharmacology (Berl). 1992; 109(4):383-9.