Ajmaline

"Ajmaline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An alkaloid found in the root of RAUWOLFIA SERPENTINA, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials.

Descriptor ID	D000404
MeSH Number(s)	D03.132.436.681.077 D03.633.100.473.402.681.077
Concept/Terms	Ajmaline Ajmaline Aritmina Aritmina Tachmalin Tachmalin Gilurtymal Gilurtymal Rauverid Rauverid Wolfina Serenol Serenol Ajmaline Hydrochloride Ajmaline Hydrochloride Cardiorythmine Cardiorythmine

Below are MeSH descriptors whose meaning is more general than "Ajmaline".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Alkaloids [D03.132]
Indole Alkaloids [D03.132.436]
Secologanin Tryptamine Alkaloids [D03.132.436.681]
Ajmaline [D03.132.436.681.077]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Indoles [D03.633.100.473]
Indole Alkaloids [D03.633.100.473.402]
Secologanin Tryptamine Alkaloids [D03.633.100.473.402.681]
Ajmaline [D03.633.100.473.402.681.077]

Below are MeSH descriptors whose meaning is related to "Ajmaline".

Below are MeSH descriptors whose meaning is more specific than "Ajmaline".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ajmaline" by people in this website by year, and whether "Ajmaline" was a major or minor topic of these publications.

Bar chart showing 11 publications over 9 distinct years, with a maximum of 3 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	2	3
2005	1	0	1
2010	1	0	1
2013	1	0	1
2015	1	0	1
2016	1	0	1
2017	0	1	1
2018	0	1	1
2020	0	1	1

Below are the most recent publications written about "Ajmaline" by people in Profiles.

Di Diego JM, Patocskai B, Barajas-Martinez H, Borb?th V, Ackerman MJ, Burashnikov A, Clatot J, Li GR, Robinson VM, Hu D, Antzelevitch C. Acacetin suppresses the electrocardiographic and arrhythmic manifestations of the J wave syndromes. PLoS One. 2020; 15(11):e0242747.

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Hasdemir C, Juang JJ, Kose S, Kocabas U, Orman MN, Payzin S, Sahin H, Celen C, Ozcan EE, Chen CJ, Gunduz R, Turan OE, Senol O, Burashnikov E, Antzelevitch C. Coexistence of atrioventricular accessory pathways and drug-induced type 1 Brugada pattern. Pacing Clin Electrophysiol. 2018 09; 41(9):1078-1092.

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Antzelevitch C, Patocskai B. Ajmaline-Induced Slowing of Conduction in the Right Ventricular Outflow Tract Cannot Account for ST Elevation in Patients With Type I Brugada ECG. Circ Arrhythm Electrophysiol. 2017 10; 10(10).

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Patocskai B, Yoon N, Antzelevitch C. Mechanisms Underlying Epicardial Radiofrequency Ablation to Suppress Arrhythmogenesis in Experimental Models of Brugada Syndrome. JACC Clin Electrophysiol. 2017 04; 3(4):353-363.

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Hasdemir C, Payzin S, Kocabas U, Sahin H, Yildirim N, Alp A, Aydin M, Pfeiffer R, Burashnikov E, Wu Y, Antzelevitch C. High prevalence of concealed Brugada syndrome in patients with atrioventricular nodal reentrant tachycardia. Heart Rhythm. 2015 Jul; 12(7):1584-94.

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Baranchuk A, Sicouri S, Elizari MV, Chiale PA. Pause-dependent normalization of ST-segment elevation during the ajmaline test in a patient with Brugada syndrome. Heart Rhythm. 2014 Apr; 11(4):707-9.

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Said SM, Husser D, Bollmann A, Piorkowski C, Braun-Dullaeus RC. [Ajmaline test]. Dtsch Med Wochenschr. 2010 Mar; 135(11):513-5.

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Wolpert C, Echternach C, Veltmann C, Antzelevitch C, Thomas GP, Spehl S, Streitner F, Kuschyk J, Schimpf R, Haase KK, Borggrefe M. Intravenous drug challenge using flecainide and ajmaline in patients with Brugada syndrome. Heart Rhythm. 2005 Mar; 2(3):254-60.

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Hong K, Brugada J, Oliva A, Berruezo-Sanchez A, Potenza D, Pollevick GD, Guerchicoff A, Matsuo K, Burashnikov E, Dumaine R, Towbin JA, Nesterenko V, Brugada P, Antzelevitch C, Brugada R. Value of electrocardiographic parameters and ajmaline test in the diagnosis of Brugada syndrome caused by SCN5A mutations. Circulation. 2004 Nov 09; 110(19):3023-7.

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Fish JM, Antzelevitch C. Role of sodium and calcium channel block in unmasking the Brugada syndrome. Heart Rhythm. 2004 Jul; 1(2):210-7.

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