"Prion Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane glycosylphosphatidylinositol-anchored glycoproteins that may aggregate into rod-like structures. The prion protein (PRNP) gene is characterized by five TANDEM REPEAT SEQUENCES that encode a highly unstable protein region of five octapeptide repeats. Mutations in the repeat region and elsewhere in this gene are associated with CREUTZFELDT-JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GERSTMANN-STRAUSSLER DISEASE; Huntington disease-like 1, and KURU.
| Descriptor ID |
D000072002
|
| MeSH Number(s) |
D12.776.395.550.448.600 D12.776.543.484.500.625 D12.776.543.550.418.600 D12.776.785.340
|
| Concept/Terms |
Prion Proteins- Prion Proteins
- Prion Protein
- CD230 Antigen
- Antigen, CD230
- PrP Proteins
- Fatal Familial Insomnia Protein
- Major Prion Protein
- Prion Protein, Major
- Creutzfeldt-Jakob Disease Protein
- Creutzfeldt Jakob Disease Protein
|
Below are MeSH descriptors whose meaning is more general than "Prion Proteins".
Below are MeSH descriptors whose meaning is more specific than "Prion Proteins".
This graph shows the total number of publications written about "Prion Proteins" by people in this website by year, and whether "Prion Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Prion Proteins" by people in Profiles.
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Ghosh S, Jana R, Jana S, Basu R, Chatterjee M, Ranawat N, Das Sarma J. Differential expression of cellular prion protein (PrPC) in mouse hepatitis virus induced neuroinflammation. J Neurovirol. 2024 06; 30(3):215-228.
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Hassan A, Quinn CM, Struppe J, Sergeyev IV, Zhang C, Guo C, Runge B, Theint T, Dao HH, Jaroniec CP, Berbon M, Lends A, Habenstein B, Loquet A, Kuemmerle R, Perrone B, Gronenborn AM, Polenova T. Sensitivity boosts by the CPMAS CryoProbe for challenging biological assemblies. J Magn Reson. 2020 02; 311:106680.
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Wu B, McDonald AJ, Markham K, Rich CB, McHugh KP, Tatzelt J, Colby DW, Millhauser GL, Harris DA. The N-terminus of the prion protein is a toxic effector regulated by the C-terminus. Elife. 2017 05 20; 6.
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Kumar N, Boeve BF, Boot BP, Orr CF, Duffy J, Woodruff BK, Nair AK, Ellison J, Kuntz K, Kantarci K, Jack CR, Westmoreland BF, Fields JA, Baker M, Rademakers R, Parisi JE, Dickson DW. Clinical characterization of a kindred with a novel 12-octapeptide repeat insertion in the prion protein gene. Arch Neurol. 2011 Sep; 68(9):1165-70.