"CD59 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)
| Descriptor ID |
D018957
|
| MeSH Number(s) |
D12.776.395.550.448.140 D12.776.543.484.500.140 D12.776.543.550.418.140
|
| Concept/Terms |
CD59 Antigens- CD59 Antigens
- Antigens, CD59
- Membrane Attack Complex Inhibition Factor
- Protectin
- MACIF
- Membrane Inhibitor of Reactive Lysis
- Homologous Restriction Factor 20
- CD59 Antigen
- HRF20
|
Below are MeSH descriptors whose meaning is more general than "CD59 Antigens".
Below are MeSH descriptors whose meaning is more specific than "CD59 Antigens".
This graph shows the total number of publications written about "CD59 Antigens" by people in this website by year, and whether "CD59 Antigens" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "CD59 Antigens" by people in Profiles.
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Bellone S, Roque D, Cocco E, Gasparrini S, Bortolomai I, Buza N, Abu-Khalaf M, Silasi DA, Ratner E, Azodi M, Schwartz PE, Rutherford TJ, Pecorelli S, Santin AD. Downregulation of membrane complement inhibitors CD55 and CD59 by siRNA sensitises uterine serous carcinoma overexpressing Her2/neu to complement and antibody-dependent cell cytotoxicity in vitro: implications for trastuzumab-based immunotherapy. Br J Cancer. 2012 Apr 24; 106(9):1543-50.
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Frankland S, Adisa A, Horrocks P, Taraschi TF, Schneider T, Elliott SR, Rogerson SJ, Knuepfer E, Cowman AF, Newbold CI, Tilley L. Delivery of the malaria virulence protein PfEMP1 to the erythrocyte surface requires cholesterol-rich domains. Eukaryot Cell. 2006 May; 5(5):849-60.
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Vedeler CA, Conti G, Fujioka T, Scarpini E, Rostami A. The expression of CD59 in experimental allergic neuritis. J Neurol Sci. 1999 Jun 01; 165(2):154-9.
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Lin SS, Weidner BC, Byrne GW, Diamond LE, Lawson JH, Hoopes CW, Daniels LJ, Daggett CW, Parker W, Harland RC, Davis RD, Bollinger RR, Logan JS, Platt JL. The role of antibodies in acute vascular rejection of pig-to-baboon cardiac transplants. J Clin Invest. 1998 Apr 15; 101(8):1745-56.