"Protein Kinase C beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
PKC beta encodes two proteins (PKCB1 and PKCBII) generated by alternative splicing of C-terminal exons. It is widely distributed with wide-ranging roles in processes such as B-cell receptor regulation, oxidative stress-induced apoptosis, androgen receptor-dependent transcriptional regulation, insulin signaling, and endothelial cell proliferation.
| Descriptor ID |
D064546
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.725.049
|
| Concept/Terms |
Protein Kinase C beta2- Protein Kinase C beta2
- PKCbeta2
- Protein Kinase C-beta(II)
- PKCBII
- PKC-beta II
- PKC beta II
- Protein Kinase C beta I
- Protein Kinase C-beta (II)
- PKC beta 2
- beta 2, PKC
- Protein Kinase C beta II
|
Below are MeSH descriptors whose meaning is more general than "Protein Kinase C beta".
Below are MeSH descriptors whose meaning is more specific than "Protein Kinase C beta".
This graph shows the total number of publications written about "Protein Kinase C beta" by people in this website by year, and whether "Protein Kinase C beta" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Protein Kinase C beta" by people in Profiles.
-
Ubba V, Gupta RK, Hakim BA, Bora HK, Sachdev M, Tripathi R, Jha RK. PKC-?II is downregulated in the premature ovarian failure SD rat model. Reprod Biol. 2023 Jun; 23(2):100754.
-
Buitrago L, Bhavanasi D, Dangelmaier C, Manne BK, Badolia R, Borgognone A, Tsygankov AY, McKenzie SE, Kunapuli SP. Tyrosine phosphorylation on spleen tyrosine kinase (Syk) is differentially regulated in human and murine platelets by protein kinase C isoforms. J Biol Chem. 2013 Oct 04; 288(40):29160-9.
-
Lei S, Li H, Xu J, Liu Y, Gao X, Wang J, Ng KF, Lau WB, Ma XL, Rodrigues B, Irwin MG, Xia Z. Hyperglycemia-induced protein kinase C ?2 activation induces diastolic cardiac dysfunction in diabetic rats by impairing caveolin-3 expression and Akt/eNOS signaling. Diabetes. 2013 Jul; 62(7):2318-28.
-
Hawcroft G, D'Amico M, Albanese C, Markham AF, Pestell RG, Hull MA. Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells. Carcinogenesis. 2002 Jan; 23(1):107-14.
-
Hirono M, Sugiyama T, Kishimoto Y, Sakai I, Miyazawa T, Kishio M, Inoue H, Nakao K, Ikeda M, Kawahara S, Kirino Y, Katsuki M, Horie H, Ishikawa Y, Yoshioka T. Phospholipase Cbeta4 and protein kinase Calpha and/or protein kinase CbetaI are involved in the induction of long term depression in cerebellar Purkinje cells. J Biol Chem. 2001 Nov 30; 276(48):45236-42.