"Jagged-1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate CELL DIFFERENTIATION in HEMATOPOIESIS and PHYSIOLOGIC ANGIOGENESIS. Mutations in the Jagged-1 gene are associated with ALAGILLE SYNDROME 1.
| Descriptor ID |
D000072100
|
| MeSH Number(s) |
D12.644.276.930.500 D12.776.157.125.797.500 D12.776.543.800.500 D23.529.930.500
|
| Concept/Terms |
Jagged-1 Protein- Jagged-1 Protein
- Jagged 1 Protein
- Alagille Syndrome Protein
- Jagged1 Protein
- Serrate1 Protein
- Jagged-1
- Jagged 1
- Serrate-1 Protein
- Serrate 1 Protein
- CD339 Antigen
- Antigen, CD339
|
Below are MeSH descriptors whose meaning is more general than "Jagged-1 Protein".
Below are MeSH descriptors whose meaning is more specific than "Jagged-1 Protein".
This graph shows the total number of publications written about "Jagged-1 Protein" by people in this website by year, and whether "Jagged-1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
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Below are the most recent publications written about "Jagged-1 Protein" by people in Profiles.
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Briot A, Jaroszewicz A, Warren CM, Lu J, Touma M, Rudat C, Hofmann JJ, Airik R, Weinmaster G, Lyons K, Wang Y, Kispert A, Pellegrini M, Iruela-Arispe ML. Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Dev Cell. 2014 Dec 22; 31(6):707-21.
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Vega ME, Giroux V, Natsuizaka M, Liu M, Klein-Szanto AJ, Stairs DB, Nakagawa H, Wang KK, Wang TC, Lynch JP, Rustgi AK. Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4. Cell Cycle. 2014; 13(24):3857-66.
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Bae Y, Yang T, Zeng HC, Campeau PM, Chen Y, Bertin T, Dawson BC, Munivez E, Tao J, Lee BH. miRNA-34c regulates Notch signaling during bone development. Hum Mol Genet. 2012 Jul 01; 21(13):2991-3000.
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Nofziger D, Miyamoto A, Lyons KM, Weinmaster G. Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts. Development. 1999 Apr; 126(8):1689-702.