"Pregabalin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gamma-aminobutyric acid (GABA) derivative that functions as a CALCIUM CHANNEL BLOCKER and is used as an ANTICONVULSANT as well as an ANTI-ANXIETY AGENT. It is also used as an ANALGESIC in the treatment of NEUROPATHIC PAIN and FIBROMYALGIA.
| Descriptor ID |
D000069583
|
| MeSH Number(s) |
D02.241.081.114.500.350.500 D12.125.190.350.450
|
| Concept/Terms |
Pregabalin- Pregabalin
- (S)-3-(aminomethyl)-5-methylhexanoic acid
- 3-isobutyl GABA
- 3 isobutyl GABA
- GABA, 3-isobutyl
- 3-(aminomethyl)-5-methylhexanoic acid
- (R-)-3-isobutyl GABA
- (S+)-3-isobutyl GABA
CI 1008- CI 1008
- 1008, CI
- CI-1008
- CI1008
|
Below are MeSH descriptors whose meaning is more general than "Pregabalin".
Below are MeSH descriptors whose meaning is more specific than "Pregabalin".
This graph shows the total number of publications written about "Pregabalin" by people in this website by year, and whether "Pregabalin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 2 | 2 |
| 2021 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pregabalin" by people in Profiles.
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Sodhi N, Qilleri A, Aprigliano C, Danoff JR. One Size Does Not Fit All: Women Experience More Pain Than Men After Total Knee Arthroplasty. J Arthroplasty. 2025 04; 40(4):880-886.
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Knorr JP, Barlow A, Reinaker TS, Zaki RF. A single dose of pre-operative pregabalin reduces post-operative opioid use after orthotopic liver transplantation. Clin Transplant. 2021 07; 35(7):e14319.
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Zangrilli J, Gouda N, Voskerijian A, Wang ML, Beredjiklian PK, Rivlin M. A Multimodal Pain Management Regimen for Open Treatment of Distal Radius Fractures: A Randomized Blinded Study. Hand (N Y). 2022 11; 17(6):1187-1193.
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Hannon CP, Fillingham YA, Browne JA, Schemitsch EH, Mullen K, Casambre F, Visvabharathy V, Hamilton WG, Della Valle CJ. The Efficacy and Safety of Gabapentinoids in Total Joint Arthroplasty: Systematic Review and Direct Meta-Analysis. J Arthroplasty. 2020 10; 35(10):2730-2738.e6.
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Campsen J, Call T, Allen CM, Presson AP, Martinez E, Rofaiel G, Kim RD. Prospective, double-blind, randomized clinical trial comparing an ERAS pathway with ketorolac and pregabalin versus standard of care plus placebo during live donor nephrectomy for kidney transplant. Am J Transplant. 2019 06; 19(6):1777-1781.
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Kurd MF, Kreitz T, Schroeder G, Vaccaro AR. The Role of Multimodal Analgesia in Spine Surgery. J Am Acad Orthop Surg. 2017 Apr; 25(4):260-268.
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Deeb S, McKeown DA, Torrance HJ, Wylie FM, Logan BK, Scott KS. Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases. J Anal Toxicol. 2014 Oct; 38(8):485-94.
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Sawan H, Chen AF, Viscusi ER, Parvizi J, Hozack WJ. Pregabalin reduces opioid consumption and improves outcome in chronic pain patients undergoing total knee arthroplasty. Phys Sportsmed. 2014 May; 42(2):10-8.
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Rayner H, Baharani J, Smith S, Suresh V, Dasgupta I. Uraemic pruritus: relief of itching by gabapentin and pregabalin. Nephron Clin Pract. 2012; 122(3-4):75-9.
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Singh NS, Paul RK, Torjman MC, Wainer IW. Gabapentin and (S)-pregabalin decrease intracellular D-serine concentrations in PC-12 cells. Neurosci Lett. 2013 Feb 22; 535:90-4.