"Baclofen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.
| Descriptor ID |
D001418
|
| MeSH Number(s) |
D02.241.081.114.500.350.100
|
| Concept/Terms |
Baclofen- Baclofen
- Baclophen
- PCP-GABA
- beta-(Aminomethyl)-4-chlorobenzenepropanoic Acid
- Chlorophenyl GABA
- GABA, Chlorophenyl
- beta-(p-Chlorophenyl)-gamma-aminobutyric Acid
Ba-34,647- Ba-34,647
- Ba34,647
- Ba-34647
- Ba34647
- CIBA-34,647-BA
- CIBA34,647BA
|
Below are MeSH descriptors whose meaning is more general than "Baclofen".
Below are MeSH descriptors whose meaning is more specific than "Baclofen".
This graph shows the total number of publications written about "Baclofen" by people in this website by year, and whether "Baclofen" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 2 | 3 |
| 2014 | 0 | 2 | 2 |
| 2015 | 2 | 1 | 3 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 5 | 5 |
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Below are the most recent publications written about "Baclofen" by people in Profiles.
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Levy KH, Yaszay B, Abel MF, Shah SA, Samdani AF, Sponseller PD. Baclofen pumps do not increase risk of complications following spinal fusion. Spine Deform. 2024 03; 12(2):473-480.
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Howard JJ, Shrader MW. Intrathecal baclofen therapy does not prevent hip displacement in children with cerebral palsy. Dev Med Child Neurol. 2023 08; 65(8):1124.
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Asma A, Howard JJ, Ulusaloglu AC, Rogers KJ, Miller F, Shrader MW. Identification of risk factors for reconstructive hip surgery after intrathecal baclofen therapy in children with cerebral palsy. Acta Orthop Traumatol Turc. 2023 May; 57(3):104-108.
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Dalakas MC. Therapies in Stiff-Person Syndrome: Advances and Future Prospects Based on Disease Pathophysiology. Neurol Neuroimmunol Neuroinflamm. 2023 05; 10(3).
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Asma A, Ulusaloglu AC, Howard JJ, Rogers KJ, McManus M, Miller F, Shrader MW. Does intrathecal baclofen therapy decrease the progression of hip displacement in young patients with cerebral palsy? Dev Med Child Neurol. 2023 08; 65(8):1112-1117.
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Ulusaloglu AC, Asma A, Rogers KJ, Shrader MW, Miller F, Howard JJ. Femoral Head Deformity Associated With Hip Displacement in Nonambulatory Cerebral Palsy: Results at Skeletal Maturity. J Pediatr Orthop. 2023 03 01; 43(3):156-161.
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Schmitz NS, Krach LE, Coles LD, Schrogie J, Cloyd JC, Kriel RL. Characterizing Baclofen Withdrawal: A National Survey of Physician Experience. Pediatr Neurol. 2021 09; 122:106-109.
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Surathi P, Sher J, Obaydou N, Pergament KM. Sepsis or sympathetics? Paroxysmal sympathetic hyperactivity after pontine stroke. BMJ Case Rep. 2021 Jul 22; 14(7).
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Imerci A, Rogers K, Dixit D, McManus M, Miller F, Sees JP. The effectiveness of epidural blood patch in patients with cerebral palsy treated with intrathecal baclofen implantation. Paediatr Anaesth. 2020 02; 30(2):153-160.
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Shenoda BB, Krevolin LE, Sherman M. Syndrome of Inappropriate Antidiuretic Hormone Release During Ketamine Infusion in Complex Regional Syndrome Patient Receiving Intrathecal Baclofen: A Case Report. A A Pract. 2019 Nov 15; 13(10):386-388.