Solute Carrier Organic Anion Transporter Family Member 1B3
"Solute Carrier Organic Anion Transporter Family Member 1B3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA.
| Descriptor ID |
D000074542
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| MeSH Number(s) |
D12.776.157.530.450.074.500.781.875 D12.776.157.530.937.905 D12.776.543.585.450.074.500.875.875 D12.776.543.585.937.950
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| Concept/Terms |
Solute Carrier Organic Anion Transporter Family Member 1B3- Solute Carrier Organic Anion Transporter Family Member 1B3
- OATP8 Protein
- Solute Carrier Family 21 Member 8 Protein
- Liver-Specific Organic Anion Transporter-2
- Liver Specific Organic Anion Transporter 2
- OATP1B3 Protein
- SLC21A8 Protein
- SLCO1B3 Protein
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Below are MeSH descriptors whose meaning is more general than "Solute Carrier Organic Anion Transporter Family Member 1B3".
Below are MeSH descriptors whose meaning is more specific than "Solute Carrier Organic Anion Transporter Family Member 1B3".
This graph shows the total number of publications written about "Solute Carrier Organic Anion Transporter Family Member 1B3" by people in this website by year, and whether "Solute Carrier Organic Anion Transporter Family Member 1B3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Solute Carrier Organic Anion Transporter Family Member 1B3" by people in Profiles.
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Dayal JH, Cole CL, Pourreyron C, Watt SA, Lim YZ, Salas-Alanis JC, Murrell DF, McGrath JA, Stieger B, Jahoda C, Leigh IM, South AP. Type VII collagen regulates expression of OATP1B3, promotes front-to-rear polarity and increases structural organisation in 3D spheroid cultures of RDEB tumour keratinocytes. J Cell Sci. 2014 Feb 15; 127(Pt 4):740-51.
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Kim KP, Ahn JH, Kim SB, Jung KH, Yoon DH, Lee JS, Ahn SH. Prospective evaluation of the drug-metabolizing enzyme polymorphisms and toxicity profile of docetaxel in Korean patients with operable lymph node-positive breast cancer receiving adjuvant chemotherapy. Cancer Chemother Pharmacol. 2012 May; 69(5):1221-7.
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Wright JL, Kwon EM, Ostrander EA, Montgomery RB, Lin DW, Vessella R, Stanford JL, Mostaghel EA. Expression of SLCO transport genes in castration-resistant prostate cancer and impact of genetic variation in SLCO1B3 and SLCO2B1 on prostate cancer outcomes. Cancer Epidemiol Biomarkers Prev. 2011 Apr; 20(4):619-27.