Vitamin D-Binding Protein

"Vitamin D-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An alpha-globulin found in the plasma of man and other vertebrates. It is apparently synthesized in the liver and carries vitamin D and its metabolites through the circulation and mediates the response of tissue. It is also known as group-specific component (Gc). Gc subtypes are used to determine specific phenotypes and gene frequencies. These data are employed in the classification of population groups, paternity investigations, and in forensic medicine.

Descriptor ID	D014809
MeSH Number(s)	D12.776.157.920
Concept/Terms	Vitamin D-Binding Protein Vitamin D-Binding Protein Vitamin D Binding Protein 25-Hydroxycholecalciferol-Binding Protein 25 Hydroxycholecalciferol Binding Protein 25-Hydroxyvitamin D-Binding Protein 25 Hydroxyvitamin D Binding Protein Vitamin D-Binding Globulin Globulin, Vitamin D-Binding Vitamin D Binding Globulin Gc Globulin Globulin, Gc Group-Specific Component Globulin Component Globulin, Group-Specific Globulin, Group-Specific Component Group Specific Component Globulin Transcalciferin 25-HCC-Binding Protein 25 HCC Binding Protein Calciferol-Binding Protein Calciferol Binding Protein

Below are MeSH descriptors whose meaning is more general than "Vitamin D-Binding Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Vitamin D-Binding Protein [D12.776.157.920]

Below are MeSH descriptors whose meaning is related to "Vitamin D-Binding Protein".

Below are MeSH descriptors whose meaning is more specific than "Vitamin D-Binding Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Vitamin D-Binding Protein" by people in this website by year, and whether "Vitamin D-Binding Protein" was a major or minor topic of these publications.

Bar chart showing 9 publications over 9 distinct years, with a maximum of 1 publications in 1997 and 2010 and 2012 and 2013 and 2015 and 2016 and 2018 and 2019 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
2010	1	0	1
2012	1	0	1
2013	0	1	1
2015	1	0	1
2016	1	0	1
2018	1	0	1
2019	1	0	1
2021	1	0	1

Below are the most recent publications written about "Vitamin D-Binding Protein" by people in Profiles.

Staquicini FI, Hajitou A, Driessen WH, Proneth B, Card?-Vila M, Staquicini DI, Markosian C, Hoh M, Cortez M, Hooda-Nehra A, Jaloudi M, Silva IT, Buttura J, Nunes DN, Dias-Neto E, Eckhardt B, Ruiz-Ram?rez J, Dogra P, Wang Z, Cristini V, Trepel M, Anderson R, Sidman RL, Gelovani JG, Cristofanilli M, Hortobagyi GN, Bhujwalla ZM, Burley SK, Arap W, Pasqualini R. Targeting a cell surface vitamin D receptor on tumor-associated macrophages in triple-negative breast cancer. Elife. 2021 06 01; 10.

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Khan AH, Jafri L, Siddiqui A, Naureen G, Morris H, Moatter T. Polymorphisms in the GC Gene for Vitamin D Binding Protein and Their Association with Vitamin D and Bone Mass in Young Adults. J Coll Physicians Surg Pak. 2019 Aug; 29(8):715-719.

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Chandler PD, Tobias DK, Wang L, Smith-Warner SA, Chasman DI, Rose L, Giovannucci EL, Buring JE, Ridker PM, Cook NR, Manson JE, Sesso HD. Association between Vitamin D Genetic Risk Score and Cancer Risk in a Large Cohort of U.S. Women. Nutrients. 2018 Jan 09; 10(1).

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Franasiak JM, Wang X, Molinaro TA, Green K, Sun W, Werner MD, Juneau CR, Scott RT. Free vitamin D does not vary through the follicular phase of the menstrual cycle. Endocrine. 2016 Jul; 53(1):322-6.

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Serce Pehlevan O, Karatekin G, Koksal V, Benzer D, Gursoy T, Yavuz T, Ovali F. Association of vitamin D binding protein polymorphisms with bronchopulmonary dysplasia: a case-control study of gc globulin and bronchopulmonary dysplasia. J Perinatol. 2015 Sep; 35(9):763-7.

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Havens PL, Kiser JJ, Stephensen CB, Hazra R, Flynn PM, Wilson CM, Rutledge B, Bethel J, Pan CG, Woodhouse LR, Van Loan MD, Liu N, Lujan-Zilbermann J, Baker A, Kapogiannis BG, Gordon CM, Mulligan K. Association of higher plasma vitamin D binding protein and lower free calcitriol levels with tenofovir disoproxil fumarate use and plasma and intracellular tenofovir pharmacokinetics: cause of a functional vitamin D deficiency? Antimicrob Agents Chemother. 2013 Nov; 57(11):5619-28.

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Engelman CD, Meyers KJ, Iyengar SK, Liu Z, Karki CK, Igo RP, Truitt B, Robinson J, Sarto GE, Wallace R, Blodi BA, Klein ML, Tinker L, LeBlanc ES, Jackson RD, Song Y, Manson JE, Mares JA, Millen AE. Vitamin D intake and season modify the effects of the GC and CYP2R1 genes on 25-hydroxyvitamin D concentrations. J Nutr. 2013 Jan; 143(1):17-26.

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Christakos S, Ajibade DV, Dhawan P, Fechner AJ, Mady LJ. Vitamin D: metabolism. Endocrinol Metab Clin North Am. 2010 Jun; 39(2):243-53, table of contents.

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Yamamoto N, Naraparaju VR, Moore M, Brent LH. Deglycosylation of serum vitamin D3-binding protein by alpha-N-acetylgalactosaminidase detected in the plasma of patients with systemic lupus erythematosus. Clin Immunol Immunopathol. 1997 Mar; 82(3):290-8.

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