"AIDS Dementia Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
| Descriptor ID |
D015526
|
| MeSH Number(s) |
C02.782.815.616.400.070 C02.800.801.400.070 C10.228.140.380.070 C20.673.480.070 F03.615.400.050
|
| Concept/Terms |
AIDS Dementia Complex- AIDS Dementia Complex
- Complex, AIDS Dementia
- Dementia Complex, AIDS
- HIV-Associated Cognitive Motor Complex
- HIV Associated Cognitive Motor Complex
- Dementia Complex, Acquired Immune Deficiency Syndrome
- Acquired-Immune Deficiency Syndrome Dementia Complex
- AIDS-Related Dementia Complex
- AIDS Related Dementia Complex
- HIV Dementia
- Dementia, HIV
- Dementias, HIV
- HIV Dementias
- Dementia Complex, AIDS-Related
- Complex, AIDS-Related Dementia
- Dementia Complex, AIDS Related
HIV Encephalopathy- HIV Encephalopathy
- Encephalopathies, HIV
- HIV Encephalopathies
- Encephalopathy, AIDS
- Encephalopathy, HIV
- AIDS Encephalopathy
- AIDS Encephalopathies
- Encephalopathies, AIDS
|
Below are MeSH descriptors whose meaning is more general than "AIDS Dementia Complex".
Below are MeSH descriptors whose meaning is more specific than "AIDS Dementia Complex".
This graph shows the total number of publications written about "AIDS Dementia Complex" by people in this website by year, and whether "AIDS Dementia Complex" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2011 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "AIDS Dementia Complex" by people in Profiles.
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Anteraper SA, Gopinath K, Hoch MJ, Waldrop-Valverde D, Franklin D, Letendre SL, Whitfield-Gabrieli S, Anderson AM. A comprehensive data-driven analysis framework for detecting impairments in brain function networks with resting state fMRI in HIV-infected individuals on cART. J Neurovirol. 2021 04; 27(2):239-248.
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Chaganti J, Marripudi K, Staub LP, Rae CD, Gates TM, Moffat KJ, Brew BJ. Imaging correlates of the blood-brain barrier disruption in HIV-associated neurocognitive disorder and therapeutic implications. AIDS. 2019 10 01; 33(12):1843-1852.
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Chaganti JR, Heinecke A, Gates TM, Moffat KJ, Brew BJ. Functional Connectivity in Virally Suppressed Patients with HIV-Associated Neurocognitive Disorder: A Resting-State Analysis. AJNR Am J Neuroradiol. 2017 Aug; 38(8):1623-1629.
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Gates TM, Cysique LA, Siefried KJ, Chaganti J, Moffat KJ, Brew BJ. Maraviroc-intensified combined antiretroviral therapy improves cognition in virally suppressed HIV-associated neurocognitive disorder. AIDS. 2016 Feb 20; 30(4):591-600.
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Steiner JP, Bachani M, Wolfson-Stofko B, Lee MH, Wang T, Wang T, Li G, Li W, Strayer D, Haughey NJ, Nath A. Interaction of paroxetine with mitochondrial proteins mediates neuroprotection. Neurotherapeutics. 2015 Jan; 12(1):200-16.
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Louboutin JP, Reyes BA, Agrawal L, Van Bockstaele EJ, Strayer DS. HIV-1 gp120 upregulates matrix metalloproteinases and their inhibitors in a rat model of HIV encephalopathy. Eur J Neurosci. 2011 Dec; 34(12):2015-23.
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Agrawal L, Louboutin JP, Reyes BA, Van Bockstaele EJ, Strayer DS. HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes. Neurobiol Dis. 2012 Feb; 45(2):657-70.
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Agrawal L, Louboutin JP, Marusich E, Reyes BA, Van Bockstaele EJ, Strayer DS. Dopaminergic neurotoxicity of HIV-1 gp120: reactive oxygen species as signaling intermediates. Brain Res. 2010 Jan 08; 1306:116-30.
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Louboutin JP, Agrawal L, Reyes BA, Van Bockstaele EJ, Strayer DS. A rat model of human immunodeficiency virus 1 encephalopathy using envelope glycoprotein gp120 expression delivered by SV40 vectors. J Neuropathol Exp Neurol. 2009 May; 68(5):456-73.
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Louboutin JP, Agrawal L, Reyes BA, Van Bockstaele EJ, Strayer DS. Protecting neurons from HIV-1 gp120-induced oxidant stress using both localized intracerebral and generalized intraventricular administration of antioxidant enzymes delivered by SV40-derived vectors. Gene Ther. 2007 Dec; 14(23):1650-61.