Alzheimer Disease

"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Descriptor ID	D000544
MeSH Number(s)	C10.228.140.380.100 C10.574.945.249 F03.615.400.100
Concept/Terms	Alzheimer Disease Alzheimer Disease Alzheimer's Disease Dementia, Senile Senile Dementia Dementia, Alzheimer Type Alzheimer Type Dementia Alzheimer-Type Dementia (ATD) Alzheimer Type Dementia (ATD) Dementia, Alzheimer-Type (ATD) Alzheimer Type Senile Dementia Primary Senile Degenerative Dementia Dementia, Primary Senile Degenerative Alzheimer Sclerosis Sclerosis, Alzheimer Alzheimer Syndrome Alzheimer Dementia Alzheimer Dementias Dementia, Alzheimer Dementias, Alzheimer Senile Dementia, Alzheimer Type Acute Confusional Senile Dementia Acute Confusional Senile Dementia Senile Dementia, Acute Confusional Dementia, Presenile Dementia, Presenile Presenile Dementia Alzheimer Disease, Late Onset Alzheimer Disease, Late Onset Late Onset Alzheimer Disease Alzheimer's Disease, Focal Onset Alzheimer's Disease, Focal Onset Focal Onset Alzheimer's Disease Familial Alzheimer Disease (FAD) Familial Alzheimer Disease (FAD) Alzheimer Disease, Familial (FAD) Alzheimer Diseases, Familial (FAD) Familial Alzheimer Diseases (FAD) Alzheimer Disease, Early Onset Alzheimer Disease, Early Onset Early Onset Alzheimer Disease Presenile Alzheimer Dementia

Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".

Diseases [C]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Brain Diseases [C10.228.140]
Dementia [C10.228.140.380]
Alzheimer Disease [C10.228.140.380.100]
Neurodegenerative Diseases [C10.574]
Tauopathies [C10.574.945]
Alzheimer Disease [C10.574.945.249]
Psychiatry and Psychology [F]
Mental Disorders [F03]
Neurocognitive Disorders [F03.615]
Dementia [F03.615.400]
Alzheimer Disease [F03.615.400.100]

Below are MeSH descriptors whose meaning is related to "Alzheimer Disease".

Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.

Bar chart showing 89 publications over 27 distinct years, with a maximum of 12 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	1	0	1
1998	1	1	2
2000	1	1	2
2001	0	1	1
2002	5	2	7
2004	1	0	1
2005	1	1	2
2007	2	0	2
2008	1	0	1
2009	4	0	4
2010	9	3	12
2011	5	3	8
2012	6	0	6
2013	3	1	4
2014	3	0	3
2015	1	0	1
2016	1	1	2
2017	1	0	1
2018	6	1	7
2019	5	0	5
2020	2	2	4
2021	5	0	5
2022	1	0	1
2023	3	0	3
2024	2	0	2
2025	1	0	1

Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.

Casten R, Kelley M, Lawal H, Lopez BL, Parks S, Perchiniak E, Rovner B. Inspiring Undergraduate Student Training in Alzheimer's Research (USTAR): Training the Next Generation of Aging Scientists. J Am Geriatr Soc. 2025 03; 73(3):894-899.

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Cheslow L, Snook AE, Waldman SA. Biomarkers for Managing Neurodegenerative Diseases. Biomolecules. 2024 03 26; 14(4).

View in: PubMed
Vera R, Hong N, Jiang B, Liang G, Eckenhoff MF, Kincaid HJ, Browne V, Chellaraj V, Gisewhite D, Greenberg M, Ranjan S, Zhu G, Wei H. Effects of Intranasal Dantrolene Nanoparticles on Brain Concentration and Behavior in PS19 Tau Transgenic Mice. J Alzheimers Dis. 2024; 98(2):549-562.

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Scopa C, Barnada SM, Cicardi ME, Singer M, Trotti D, Trizzino M. JUN upregulation drives aberrant transposable element mobilization, associated innate immune response, and impaired neurogenesis in Alzheimer's disease. Nat Commun. 2023 12 04; 14(1):8021.

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Ranganathan S, Abramov D, Chew NWS, Mallen C, Marshall M, Kobo O, Mamas MA. Trends in Cardiovascular Mortality Among Patients With Alzheimer's Disease in the United States from 1999 to 2020. Am J Cardiol. 2024 01 15; 211:326-333.

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Jutkowitz E, Pizzi LT, Shewmaker P, Alarid-Escudero F, Epstein-Lubow G, Prioli KM, Gaugler JE, Gitlin LN. Cost effectiveness of non-drug interventions that reduce nursing home admissions for people living with dementia. Alzheimers Dement. 2023 09; 19(9):3867-3893.

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Chen PC, Han X, Shaw TI, Fu Y, Sun H, Niu M, Wang Z, Jiao Y, Teubner BJW, Eddins D, Beloate LN, Bai B, Mertz J, Li Y, Cho JH, Wang X, Wu Z, Liu D, Poudel S, Yuan ZF, Mancieri A, Low J, Lee HM, Patton MH, Earls LR, Stewart E, Vogel P, Hui Y, Wan S, Bennett DA, Serrano GE, Beach TG, Dyer MA, Smeyne RJ, Moldoveanu T, Chen T, Wu G, Zakharenko SS, Yu G, Peng J. Alzheimer's disease-associated U1 snRNP splicing dysfunction causes neuronal hyperexcitability and cognitive impairment. Nat Aging. 2022 10; 2(10):923-940.

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Zhang L, Xie D, Li Y, Camargo A, Song D, Lu T, Jeudy J, Dreizin D, Melhem ER, Wang Z. Improving Sensitivity of Arterial Spin Labeling Perfusion MRI in Alzheimer's Disease Using Transfer Learning of Deep Learning-Based ASL Denoising. J Magn Reson Imaging. 2022 06; 55(6):1710-1722.

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Angelo M, Ward L. Aducanumab Fails to Produce Efficacy Results Yet Obtains US Food and Drug Administration Approval. Popul Health Manag. 2021 12; 24(6):638-639.

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Liu L, Volpe SL, Ross JA, Grimm JA, Van Bockstaele EJ, Eisen HJ. Dietary sugar intake and risk of Alzheimer's disease in older women. Nutr Neurosci. 2022 Nov; 25(11):2302-2313.

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