CD4 Antigens

"CD4 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.

Descriptor ID	D015704
MeSH Number(s)	D12.776.543.750.705.852.420.810.500 D12.776.543.750.830.700.025 D23.050.301.264.894.100 D23.101.100.894.100
Concept/Terms	CD4 Antigens CD4 Antigens Antigens, CD4 CD4 Molecule T4 Antigens, T-Cell Antigens, T-Cell T4 T-Cell T4 Antigens T4 Antigens, T Cell Receptors, CD4 Surface CD4 Receptor CD4 Receptor, Surface Receptors, Surface CD4 CD4 Receptors, Surface Surface CD4 Receptors CD4 Antigen Antigen, CD4 CD4 Receptors

Below are MeSH descriptors whose meaning is more general than "CD4 Antigens".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Interleukin [D12.776.543.750.705.852.420]
Receptors, Interleukin-16 [D12.776.543.750.705.852.420.810]
CD4 Antigens [D12.776.543.750.705.852.420.810.500]
Receptors, Virus [D12.776.543.750.830]
Receptors, HIV [D12.776.543.750.830.700]
CD4 Antigens [D12.776.543.750.830.700.025]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Surface [D23.050.301]
Antigens, Differentiation [D23.050.301.264]
Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
CD4 Antigens [D23.050.301.264.894.100]
Biomarkers [D23.101]
Antigens, Differentiation [D23.101.100]
Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
CD4 Antigens [D23.101.100.894.100]

Below are MeSH descriptors whose meaning is more specific than "CD4 Antigens".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "CD4 Antigens" by people in this website by year, and whether "CD4 Antigens" was a major or minor topic of these publications.

Bar chart showing 50 publications over 21 distinct years, with a maximum of 6 publications in 1996 and 1997

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	4	6
1997	0	6	6
1998	0	3	3
1999	0	1	1
2000	0	3	3
2001	0	2	2
2002	4	1	5
2003	0	1	1
2004	0	2	2
2005	1	0	1
2006	2	2	4
2007	1	0	1
2008	1	2	3
2009	0	1	1
2010	1	1	2
2012	0	1	1
2013	0	3	3
2015	1	0	1
2016	0	1	1
2017	0	2	2
2020	1	0	1

Below are the most recent publications written about "CD4 Antigens" by people in Profiles.

Chakravarty D, Saadi F, Kundu S, Bose A, Khan R, Dine K, Kenyon LC, Shindler KS, Das Sarma J. CD4 Deficiency Causes Poliomyelitis and Axonal Blebbing in Murine Coronavirus-Induced Neuroinflammation. J Virol. 2020 07 01; 94(14).

View in: PubMed
Zhou F, Zhang GX, Rostami A. LPS-treated bone marrow-derived dendritic cells induce immune tolerance through modulating differentiation of CD4+ regulatory T cell subpopulations mediated by 3G11 and CD127. Immunol Res. 2017 06; 65(3):630-638.

View in: PubMed
Yadav SK, Gupta RK, Garg RK, Venkatesh V, Gupta PK, Singh AK, Hashem S, Al-Sulaiti A, Kaura D, Wang E, Marincola FM, Haris M. Altered structural brain changes and neurocognitive performance in pediatric HIV. Neuroimage Clin. 2017; 14:316-322.

View in: PubMed
Tao Y, Zhang X, Markovic-Plese S. Toll-like receptor (TLR)7 and TLR9 agonists enhance interferon (IFN) beta-1a's immunoregulatory effects on B cells in patients with relapsing-remitting multiple sclerosis (RRMS). J Neuroimmunol. 2016 09 15; 298:181-8.

View in: PubMed
Hsiao C, Liu M, Stanton R, McGee M, Qian Y, Scheuermann RH. Mapping cell populations in flow cytometry data for cross-sample comparison using the Friedman-Rafsky test statistic as a distance measure. Cytometry A. 2016 Jan; 89(1):71-88.

View in: PubMed
Simpson TR, Li F, Montalvo-Ortiz W, Sepulveda MA, Bergerhoff K, Arce F, Roddie C, Henry JY, Yagita H, Wolchok JD, Peggs KS, Ravetch JV, Allison JP, Quezada SA. Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma. J Exp Med. 2013 Aug 26; 210(9):1695-710.

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Fernandez SV, Robertson FM, Pei J, Aburto-Chumpitaz L, Mu Z, Chu K, Alpaugh RK, Huang Y, Cao Y, Ye Z, Cai KQ, Boley KM, Klein-Szanto AJ, Devarajan K, Addya S, Cristofanilli M. Inflammatory breast cancer (IBC): clues for targeted therapies. Breast Cancer Res Treat. 2013 Jul; 140(1):23-33.

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Gruell H, Bournazos S, Ravetch JV, Ploss A, Nussenzweig MC, Pietzsch J. Antibody and antiretroviral preexposure prophylaxis prevent cervicovaginal HIV-1 infection in a transgenic mouse model. J Virol. 2013 Aug; 87(15):8535-44.

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Danial M, Root MJ, Klok HA. Polyvalent side chain peptide-synthetic polymer conjugates as HIV-1 entry inhibitors. Biomacromolecules. 2012 May 14; 13(5):1438-47.

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Magro CM, Porcu P, Schaefer J, Erter JW, Furman RR, Shitabata PK, Crowson AN. Cutaneous CD4+ CD56+ hematologic malignancies. J Am Acad Dermatol. 2010 Aug; 63(2):292-308.

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