Fibroblast Growth Factor 1
"Fibroblast Growth Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2).
| Descriptor ID |
D016220
|
| MeSH Number(s) |
D12.644.276.624.110 D12.776.467.624.110 D23.529.624.110
|
| Concept/Terms |
Fibroblast Growth Factor 1- Fibroblast Growth Factor 1
- HBGF-1
- Heparin-Binding Fibroblast Growth Factor Class I
- Heparin-Binding Growth Factor, Class I
- Heparin Binding Growth Factor, Class I
- Fibroblast Growth Factor, Acidic
- Fibroblast Growth Factor-1
- Class I Heparin-Binding Growth Factor
- FGF-1
- FGF1
- Acidic Fibroblast Growth Factor
|
Below are MeSH descriptors whose meaning is more general than "Fibroblast Growth Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Fibroblast Growth Factor 1".
This graph shows the total number of publications written about "Fibroblast Growth Factor 1" by people in this website by year, and whether "Fibroblast Growth Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fibroblast Growth Factor 1" by people in Profiles.
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Tamura I, Chaqour B, Howard PS, Ikeo T, Macarak EJ. Effect of fibroblast growth factor-1 on the expression of early growth response-1 in human periodontal ligament cells. J Periodontal Res. 2008 Jun; 43(3):305-10.
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Rosini P, Bonaccorsi L, Baldi E, Chiasserini C, Forti G, De Chiara G, Lucibello M, Mongiat M, Iozzo RV, Garaci E, Cozzolino F, Torcia MG. Androgen receptor expression induces FGF2, FGF-binding protein production, and FGF2 release in prostate carcinoma cells: role of FGF2 in growth, survival, and androgen receptor down-modulation. Prostate. 2002 Dec 01; 53(4):310-21.
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Ghiselli G, Eichstetter I, Iozzo RV. A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor. Biochem J. 2001 Oct 01; 359(Pt 1):153-63.
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McAndrew PE, Frostholm A, Evans JE, Zdilar D, Goldowitz D, Chiu IM, Burghes AH, Rotter A. Novel receptor protein tyrosine phosphatase (RPTPrho) and acidic fibroblast growth factor (FGF-1) transcripts delineate a rostrocaudal boundary in the granule cell layer of the murine cerebellar cortex. J Comp Neurol. 1998 Feb 22; 391(4):444-55.
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Hitraya EG, Tan EM, Rudnicka L, Jimenez SA. Expression of extracellular matrix genes in adult human dermal microvascular endothelial cells and their regulation by heparin and endothelial cell mitogens. Lab Invest. 1995 Sep; 73(3):393-402.
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Bjornsson TD, Dryjski M, Tluczek J, Mennie R, Ronan J, Mellin TN, Thomas KA. Acidic fibroblast growth factor promotes vascular repair. Proc Natl Acad Sci U S A. 1991 Oct 01; 88(19):8651-5.