Amyloid beta-Peptides

"Amyloid beta-Peptides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Peptides generated from AMYLOID BETA-PEPTIDES PRECURSOR. An amyloid fibrillar form of these peptides is the major component of amyloid plaques found in individuals with Alzheimer's disease and in aged individuals with trisomy 21 (DOWN SYNDROME). The peptide is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue.

Descriptor ID	D016229
MeSH Number(s)	D12.644.024 D12.776.049.407.249.500 D12.776.543.039.500
Concept/Terms	Amyloid beta-Peptides Amyloid beta-Peptides Amyloid beta Peptides beta-Peptides, Amyloid Alzheimer's ABP ABP, Alzheimer's Alzheimer ABP Alzheimers ABP Alzheimer's Amyloid Fibril Protein Amyloid AD-AP AD-AP, Amyloid Amyloid AD AP beta-Amyloid Protein Protein, beta-Amyloid beta Amyloid Protein Amyloid beta-Protein Amyloid beta Protein beta-Protein, Amyloid Amyloid beta-Proteins Amyloid beta Proteins beta-Proteins, Amyloid Amyloid Fibril Protein, Alzheimer's Amyloid Protein A4 Protein A4, Amyloid Alzheimer beta-Protein Alzheimer beta Protein beta-Protein, Alzheimer Amyloid beta-Peptide Amyloid beta Peptide beta-Peptide, Amyloid

Below are MeSH descriptors whose meaning is more general than "Amyloid beta-Peptides".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Amyloid beta-Peptides [D12.644.024]
Proteins [D12.776]
Amyloid [D12.776.049]
Amyloidogenic Proteins [D12.776.049.407]
Amyloid beta-Protein Precursor [D12.776.049.407.249]
Amyloid beta-Peptides [D12.776.049.407.249.500]
Membrane Proteins [D12.776.543]
Amyloid beta-Protein Precursor [D12.776.543.039]
Amyloid beta-Peptides [D12.776.543.039.500]

Below are MeSH descriptors whose meaning is related to "Amyloid beta-Peptides".

Below are MeSH descriptors whose meaning is more specific than "Amyloid beta-Peptides".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Amyloid beta-Peptides" by people in this website by year, and whether "Amyloid beta-Peptides" was a major or minor topic of these publications.

Bar chart showing 22 publications over 14 distinct years, with a maximum of 3 publications in 2013 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
1998	0	1	1
2004	1	1	2
2005	1	0	1
2008	2	0	2
2009	1	0	1
2010	0	1	1
2013	1	2	3
2015	1	1	2
2016	1	0	1
2018	2	1	3
2019	1	1	2
2020	1	0	1
2023	0	1	1

Below are the most recent publications written about "Amyloid beta-Peptides" by people in Profiles.

Scopa C, Barnada SM, Cicardi ME, Singer M, Trotti D, Trizzino M. JUN upregulation drives aberrant transposable element mobilization, associated innate immune response, and impaired neurogenesis in Alzheimer's disease. Nat Commun. 2023 12 04; 14(1):8021.

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Maulik M, Vasan L, Bose A, Dutta Chowdhury S, Sengupta N, Das Sarma J. Amyloid-? regulates gap junction protein connexin 43 trafficking in cultured primary astrocytes. J Biol Chem. 2020 10 30; 295(44):15097-15111.

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Vosoughi A, Sadigh-Eteghad S, Ghorbani M, Shahmorad S, Farhoudi M, Rafi MA, Omidi Y. Mathematical Models to Shed Light on Amyloid-Beta and Tau Protein Dependent Pathologies in Alzheimer's Disease. Neuroscience. 2020 01 01; 424:45-57.

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Olsson B, Portelius E, Cullen NC, Sandelius ?, Zetterberg H, Andreasson U, H?glund K, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk D, McCluskey L, Elman L, Shaw LM, Toledo JB, McBride J, Hernandez-Con P, Lee VM, Trojanowski JQ, Blennow K. Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders. JAMA Neurol. 2019 03 01; 76(3):318-325.

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Pradier L, Blanchard-Br?geon V, Bohme A, Debeir T, Menager J, Benoit P, Barneoud P, Taupin V, Bertrand P, Dugay P, Cameron B, Shi Y, Naimi S, Duchesne M, Gagnaire M, Weeden T, Travaline T, Reczek D, Khiroug L, Slaoui M, Brunel P, Fukuyama H, Ravetch J, Canton T, Cohen C. SAR228810: an antibody for protofibrillar amyloid ? peptide designed to reduce the risk of amyloid-related imaging abnormalities (ARIA). Alzheimers Res Ther. 2018 11 28; 10(1):117.

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Sandelius ?, Portelius E, K?ll?n ?, Zetterberg H, Rot U, Olsson B, Toledo JB, Shaw LM, Lee VMY, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk DA, McCluskey L, Elman L, Kostanjevecki V, Vandijck M, McBride J, Trojanowski JQ, Blennow K. Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology. Alzheimers Dement. 2019 01; 15(1):55-64.

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Portelius E, Olsson B, H?glund K, Cullen NC, Kvartsberg H, Andreasson U, Zetterberg H, Sandelius ?, Shaw LM, Lee VMY, Irwin DJ, Grossman M, Weintraub D, Chen-Plotkin A, Wolk DA, McCluskey L, Elman L, McBride J, Toledo JB, Trojanowski JQ, Blennow K. Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology. Acta Neuropathol. 2018 09; 136(3):363-376.

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Miyagawa T, Ebinuma I, Morohashi Y, Hori Y, Young Chang M, Hattori H, Maehara T, Yokoshima S, Fukuyama T, Tsuji S, Iwatsubo T, Prendergast GC, Tomita T. BIN1 regulates BACE1 intracellular trafficking and amyloid-? production. Hum Mol Genet. 2016 07 15; 25(14):2948-2958.

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Haris M, Yadav SK, Rizwan A, Singh A, Cai K, Kaura D, Wang E, Davatzikos C, Trojanowski JQ, Melhem ER, Marincola FM, Borthakur A. T1rho MRI and CSF biomarkers in diagnosis of Alzheimer's disease. Neuroimage Clin. 2015; 7:598-604.

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Carriba P, Jimenez S, Navarro V, Moreno-Gonzalez I, Barneda-Zahonero B, Moubarak RS, Lopez-Soriano J, Gutierrez A, Vitorica J, Comella JX. Amyloid-? reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFa from neuronal protection to death. Cell Death Dis. 2015 Feb 12; 6:e1639.

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