Cross-Over Studies

"Cross-Over Studies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)

Descriptor ID	D018592
MeSH Number(s)	E05.318.780.150 N05.715.360.780.150 N06.850.520.445.150
Concept/Terms	Cross-Over Studies Cross-Over Studies Cross Over Studies Cross-Over Study Studies, Cross-Over Study, Cross-Over Crossover Studies Crossover Study Studies, Crossover Study, Crossover Cross-Over Trials Cross Over Trials Trial, Cross-Over Trials, Cross-Over Crossover Trials Trial, Crossover Trials, Crossover Cross-Over Design Cross-Over Design Cross Over Design Cross-Over Designs Design, Cross-Over Designs, Cross-Over Crossover Design Crossover Designs Design, Crossover Designs, Crossover

Below are MeSH descriptors whose meaning is more general than "Cross-Over Studies".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Epidemiologic Methods [E05.318]
Epidemiologic Research Design [E05.318.780]
Cross-Over Studies [E05.318.780.150]
Health Care [N]
Health Care Quality, Access, and Evaluation [N05]
Quality of Health Care [N05.715]
Health Care Evaluation Mechanisms [N05.715.360]
Epidemiologic Research Design [N05.715.360.780]
Cross-Over Studies [N05.715.360.780.150]
Environment and Public Health [N06]
Public Health [N06.850]
Epidemiologic Methods [N06.850.520]
Epidemiologic Research Design [N06.850.520.445]
Cross-Over Studies [N06.850.520.445.150]

Below are MeSH descriptors whose meaning is related to "Cross-Over Studies".

Below are MeSH descriptors whose meaning is more specific than "Cross-Over Studies".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cross-Over Studies" by people in this website by year, and whether "Cross-Over Studies" was a major or minor topic of these publications.

Bar chart showing 259 publications over 30 distinct years, with a maximum of 22 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	0	5	5
1998	0	3	3
1999	0	5	5
2000	0	9	9
2001	0	9	9
2002	0	4	4
2003	0	8	8
2004	0	10	10
2005	0	8	8
2006	0	10	10
2007	0	11	11
2008	0	8	8
2009	0	14	14
2010	0	4	4
2011	1	9	10
2012	0	9	9
2013	0	14	14
2014	0	10	10
2015	0	6	6
2016	0	14	14
2017	0	13	13
2018	0	10	10
2019	0	22	22
2020	0	14	14
2021	0	10	10
2022	0	6	6
2023	0	3	3
2024	6	2	8
2025	0	1	1

Below are the most recent publications written about "Cross-Over Studies" by people in Profiles.

Ishigami J, Liu H, Zhao D, Sabit A, Pathiravasan CH, Charleston J, Miller ER, Matsushita K, Appel LJ, Brady TM. Effects of Noise and Public Setting on Blood Pressure Readings : A Randomized Crossover Trial. Ann Intern Med. 2025 02; 178(2):149-156.

View in: PubMed
Liu H, Zhao D, Sabit A, Pathiravasan CH, Ishigami J, Charleston J, Miller ER, Matsushita K, Appel LJ, Brady TM. Arm Position and Blood Pressure Readings: The ARMS Crossover Randomized Clinical Trial. JAMA Intern Med. 2024 12 01; 184(12):1436-1442.

View in: PubMed
Czulada E, Smith JD, Kolm P, Deb B, Dolman SF, Alexander N, Braun RA, Kabadi RA, Weintraub WS, Strouse D, Thomaides A. Rationale and Design of OPT-RATE AF: A Randomized Clinical Trial of Increased Physiologic Pacing Rates in Heart Failure With Preserved Ejection Fraction. Am J Cardiol. 2025 01 01; 234:1-8.

View in: PubMed
Barfield M, Winokur R, Berland T, Davis S, Ralph V, Chatham N, Rockson S, Maldonado TS. Results from a comparative study to evaluate the treatment effectiveness of a nonpneumatic compression device vs an advanced pneumatic compression device for lower extremity lymphedema swelling (TEAYS study). J Vasc Surg Venous Lymphat Disord. 2025 01; 13(1):101965.

View in: PubMed
Lipton RB, Harriott AM, Ma JY, Smith JH, Stokes J, Gandhi P, Jariwala-Parikh K, Jensen GS, Trugman JM, Dodick DW. Effect of Ubrogepant on Patient-Reported Outcomes When Administered During the Migraine Prodrome: Results From the Randomized PRODROME Trial. Neurology. 2024 Sep 24; 103(6):e209745.

View in: PubMed
Al-Khazali HM, Christensen RH, Dodick DW, Chaudhry BA, Melchior AG, Burstein R, Ashina H. Hypersensitivity to BKCa channel opening in persistent post-traumatic headache. J Headache Pain. 2024 Jun 18; 25(1):102.

View in: PubMed
Wen T, Puett RC, Liao D, Kanter J, Mittleman MA, Lanzkron SM, Yanosky JD. Short-term air pollution levels and sickle cell disease hospital encounters in South Carolina: A case-crossover analysis. Environ Res. 2024 07 01; 252(Pt 1):118766.

View in: PubMed
Lam K, Kraft WK, Zhan T, Lam E. Bidirectional pharmacokinetics of doravirine, tenofovir, and feminizing hormones in transgender women (IDentify): A randomized crossover trial. Clin Transl Sci. 2024 03; 17(3):e13721.

View in: PubMed
Falchook G, Patnaik A, Richardson DL, Harvey RD, Sharma MR, Hafez N, Hamilton E, Piha-Paul SA, Barve M, Wise-Draper T, Patel MR, Dowlati A, Pascuzzo J, Tang SC, Faltermeier C, Malinowska IA, Shtessel L, Striha A, Potocka E. A Relative Bioavailability, Bioequivalence, and Food Effect Study of Niraparib Tablets in Patients with Advanced Solid Tumors. Clin Ther. 2024 03; 46(3):228-238.

View in: PubMed
Dodick DW, Goadsby PJ, Schwedt TJ, Lipton RB, Liu C, Lu K, Yu SY, Severt L, Finnegan M, Trugman JM. Ubrogepant for the treatment of migraine attacks during the prodrome: a phase 3, multicentre, randomised, double-blind, placebo-controlled, crossover trial in the USA. Lancet. 2023 12 16; 402(10419):2307-2316.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement