Cross-Over Studies

"Cross-Over Studies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)

Descriptor ID	D018592
MeSH Number(s)	E05.318.780.150 N05.715.360.780.150 N06.850.520.445.150
Concept/Terms	Cross-Over Studies Cross-Over Studies Cross Over Studies Cross-Over Study Studies, Cross-Over Study, Cross-Over Crossover Studies Crossover Study Studies, Crossover Study, Crossover Cross-Over Trials Cross Over Trials Trial, Cross-Over Trials, Cross-Over Crossover Trials Trial, Crossover Trials, Crossover Cross-Over Design Cross-Over Design Cross Over Design Cross-Over Designs Design, Cross-Over Designs, Cross-Over Crossover Design Crossover Designs Design, Crossover Designs, Crossover

Below are MeSH descriptors whose meaning is more general than "Cross-Over Studies".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Epidemiologic Methods [E05.318]
Epidemiologic Research Design [E05.318.780]
Cross-Over Studies [E05.318.780.150]
Health Care [N]
Health Care Quality, Access, and Evaluation [N05]
Quality of Health Care [N05.715]
Health Care Evaluation Mechanisms [N05.715.360]
Epidemiologic Research Design [N05.715.360.780]
Cross-Over Studies [N05.715.360.780.150]
Environment and Public Health [N06]
Public Health [N06.850]
Epidemiologic Methods [N06.850.520]
Epidemiologic Research Design [N06.850.520.445]
Cross-Over Studies [N06.850.520.445.150]

Below are MeSH descriptors whose meaning is related to "Cross-Over Studies".

Below are MeSH descriptors whose meaning is more specific than "Cross-Over Studies".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cross-Over Studies" by people in this website by year, and whether "Cross-Over Studies" was a major or minor topic of these publications.

Bar chart showing 158 publications over 29 distinct years, with a maximum of 13 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	0	2	2
1999	0	3	3
2000	0	5	5
2001	0	6	6
2002	0	3	3
2003	0	8	8
2004	0	6	6
2005	0	5	5
2006	0	4	4
2007	0	5	5
2008	0	6	6
2009	0	6	6
2010	0	1	1
2011	0	7	7
2012	0	7	7
2013	0	9	9
2014	0	8	8
2015	0	4	4
2016	0	9	9
2017	0	9	9
2018	0	4	4
2019	0	13	13
2020	0	12	12
2021	0	5	5
2022	0	4	4
2023	0	2	2
2024	3	0	3
2025	0	1	1

Below are the most recent publications written about "Cross-Over Studies" by people in Profiles.

Ishigami J, Liu H, Zhao D, Sabit A, Pathiravasan CH, Charleston J, Miller ER, Matsushita K, Appel LJ, Brady TM. Effects of Noise and Public Setting on Blood Pressure Readings : A Randomized Crossover Trial. Ann Intern Med. 2025 02; 178(2):149-156.

View in: PubMed
Liu H, Zhao D, Sabit A, Pathiravasan CH, Ishigami J, Charleston J, Miller ER, Matsushita K, Appel LJ, Brady TM. Arm Position and Blood Pressure Readings: The ARMS Crossover Randomized Clinical Trial. JAMA Intern Med. 2024 12 01; 184(12):1436-1442.

View in: PubMed
Czulada E, Smith JD, Kolm P, Deb B, Dolman SF, Alexander N, Braun RA, Kabadi RA, Weintraub WS, Strouse D, Thomaides A. Rationale and Design of OPT-RATE AF: A Randomized Clinical Trial of Increased Physiologic Pacing Rates in Heart Failure With Preserved Ejection Fraction. Am J Cardiol. 2025 01 01; 234:1-8.

View in: PubMed
Wen T, Puett RC, Liao D, Kanter J, Mittleman MA, Lanzkron SM, Yanosky JD. Short-term air pollution levels and sickle cell disease hospital encounters in South Carolina: A case-crossover analysis. Environ Res. 2024 07 01; 252(Pt 1):118766.

View in: PubMed
Ishigami J, Charleston J, Miller ER, Matsushita K, Appel LJ, Brady TM. Effects of Cuff Size on the Accuracy of Blood Pressure Readings: The Cuff(SZ) Randomized Crossover Trial. JAMA Intern Med. 2023 10 01; 183(10):1061-1068.

View in: PubMed
Sideri Gugger A, Dimino C, Panigrahi SK, Mayer L, Smiley RM, Korner J, Wardlaw SL. Defining Predictors of Weight Loss Response to Lorcaserin. J Clin Endocrinol Metab. 2023 08 18; 108(9):2262-2271.

View in: PubMed
Adams JA, Lopez JR, Nadkarni V, Zolkipli-Cunningham Z, Ischiropoulos H, Sackner MA. The effects of a motorized passive simulated jogging device on descent of the arterial pulse waveform dicrotic notch: A single arm placebo-controlled cross-over trial. Physiol Rep. 2022 08; 10(15):e15418.

View in: PubMed
Barnett AM, Babcock MC, Watso JC, Migdal KU, Guti?rrez OM, Farquhar WB, Robinson AT. High dietary salt intake increases urinary NGAL excretion and creatinine clearance in healthy young adults. Am J Physiol Renal Physiol. 2022 04 01; 322(4):F392-F402.

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Kim H, Lichtenstein AH, White K, Wong KE, Miller ER, Coresh J, Appel LJ, Rebholz CM. Plasma Metabolites Associated with a Protein-Rich Dietary Pattern: Results from the OmniHeart Trial. Mol Nutr Food Res. 2022 03; 66(6):e2100890.

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Gilman JM, Schmitt WA, Potter K, Kendzior B, Pachas GN, Hickey S, Makary M, Huestis MA, Evins AE. Identification of ?9-tetrahydrocannabinol (THC) impairment using functional brain imaging. Neuropsychopharmacology. 2022 03; 47(4):944-952.

View in: PubMed

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