"Tankyrases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of telomere associated proteins that interact with TRF1 PROTEIN, contain ANKYRIN REPEATS and have poly(ADP-ribose) polymerase activity.
| Descriptor ID |
D038501
|
| MeSH Number(s) |
D08.811.913.400.725.115.690.840
|
| Concept/Terms |
Tankyrases- Tankyrases
- TRF-1 Interacting, Ankyrin-Related, ADP-Ribose Polymerases
|
Below are MeSH descriptors whose meaning is more general than "Tankyrases".
Below are MeSH descriptors whose meaning is more specific than "Tankyrases".
This graph shows the total number of publications written about "Tankyrases" by people in this website by year, and whether "Tankyrases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tankyrases" by people in Profiles.
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Langelier MF, Mirhasan M, Gilbert K, Sverzhinksy A, Furtos A, Pascal JM. PARP enzyme de novo synthesis of protein-free poly(ADP-ribose). Mol Cell. 2024 Dec 19; 84(24):4758-4773.e6.
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Koirala S, Klein J, Zheng Y, Glenn NO, Eisemann T, Fon Tacer K, Miller DJ, Kulak O, Lu M, Finkelstein DB, Neale G, Tillman H, Vogel P, Strand DW, Lum L, Brautigam CA, Pascal JM, Clements WK, Potts PR. Tissue-Specific Regulation of the Wnt/?-Catenin Pathway by PAGE4 Inhibition of Tankyrase. Cell Rep. 2020 07 21; 32(3):107922.
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Eisemann T, Pascal JM. Poly(ADP-ribose) polymerase enzymes and the maintenance of genome integrity. Cell Mol Life Sci. 2020 Jan; 77(1):19-33.
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Eisemann T, Langelier MF, Pascal JM. Structural and functional analysis of parameters governing tankyrase-1 interaction with telomeric repeat-binding factor 1 and GDP-mannose 4,6-dehydratase. J Biol Chem. 2019 10 04; 294(40):14574-14590.
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Langelier MF, Eisemann T, Riccio AA, Pascal JM. PARP family enzymes: regulation and catalysis of the poly(ADP-ribose) posttranslational modification. Curr Opin Struct Biol. 2018 12; 53:187-198.
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Fan C, Yarravarapu N, Chen H, Kulak O, Dasari P, Herbert J, Yamaguchi K, Lum L, Zhang X. Regulation of tankyrase activity by a catalytic domain dimer interface. Biochem Biophys Res Commun. 2018 09 10; 503(3):1780-1785.
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Eisemann T, McCauley M, Langelier MF, Gupta K, Roy S, Van Duyne GD, Pascal JM. Tankyrase-1 Ankyrin Repeats Form an Adaptable Binding Platform for Targets of ADP-Ribose Modification. Structure. 2016 Oct 04; 24(10):1679-1692.
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Riccio AA, McCauley M, Langelier MF, Pascal JM. Tankyrase Sterile a Motif Domain Polymerization Is Required for Its Role in Wnt Signaling. Structure. 2016 09 06; 24(9):1573-81.
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Kulak O, Chen H, Holohan B, Wu X, He H, Borek D, Otwinowski Z, Yamaguchi K, Garofalo LA, Ma Z, Wright W, Chen C, Shay JW, Zhang X, Lum L. Disruption of Wnt/?-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol Cell Biol. 2015 Jul; 35(14):2425-35.
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Karlberg T, Langelier MF, Pascal JM, Sch?ler H. Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling. Mol Aspects Med. 2013 Dec; 34(6):1088-108.