"Bethanechol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
| Descriptor ID |
D018723
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| MeSH Number(s) |
D02.092.877.883.088.100 D02.241.081.251.133.100 D02.675.276.148.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Bethanechol".
Below are MeSH descriptors whose meaning is more specific than "Bethanechol".
This graph shows the total number of publications written about "Bethanechol" by people in this website by year, and whether "Bethanechol" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
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Below are the most recent publications written about "Bethanechol" by people in Profiles.
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Singh J, Cohen S, Mehendiratta V, Mendoza F, Jimenez SA, Dimarino AJ, Rattan S. Effects of scleroderma antibodies and pooled human immunoglobulin on anal sphincter and colonic smooth muscle function. Gastroenterology. 2012 Nov; 143(5):1308-1318.
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Singh J, Rattan S. Bioengineered human IAS reconstructs with functional and molecular properties similar to intact IAS. Am J Physiol Gastrointest Liver Physiol. 2012 Sep 15; 303(6):G713-22.
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Singh J, Mehendiratta V, Del Galdo F, Jimenez SA, Cohen S, DiMarino AJ, Rattan S. Immunoglobulins from scleroderma patients inhibit the muscarinic receptor activation in internal anal sphincter smooth muscle cells. Am J Physiol Gastrointest Liver Physiol. 2009 Dec; 297(6):G1206-13.
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Miller TL, Singhaus CJ, Sherman TI, Greenspan JS, Shaffer TH. Physiologic implications of helium as a carrier gas for inhaled nitric oxide in a neonatal model of Bethanecol-induced bronchoconstriction. Pediatr Crit Care Med. 2006 Mar; 7(2):159-64.
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Dimarino M, Banwait K, Rattan S, Cohen S, DiMarino AJ. Beta3 adrenergic stimulation inhibits the opossum lower esophageal sphincter. Gastroenterology. 2002 Nov; 123(5):1508-15.
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Koo HP, Macarak EJ, Zderic SA, Duckett JW, Synder HM, Levin RM. The ontogeny of bladder function in the fetal calf. J Urol. 1995 Jul; 154(1):283-7.
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Paul DA, Ierardi JA, Parkman HP, Ryan JP. Developmental changes in gastric fundus smooth muscle contractility and involvement of extracellular calcium in fetal and adult guinea pigs. Pediatr Res. 1994 Nov; 36(5):642-6.
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Lee JG, Coplen D, Macarak E, Wein AJ, Levin RM. Comparative studies on the ontogeny and autonomic responses of the fetal calf bladder at different stages of development: involvement of nitric oxide on field stimulated relaxation. J Urol. 1994 Apr; 151(4):1096-101.
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Lee JG, Macarak E, Coplen D, Wein AJ, Levin RM. Distribution and function of the adrenergic and cholinergic receptors in the fetal calf bladder during mid-gestational age. Neurourol Urodyn. 1993; 12(6):599-607.
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Bhutani VK, Koslo RJ, Shaffer TH. The effect of tracheal smooth muscle tone on neonatal airway collapsibility. Pediatr Res. 1986 Jun; 20(6):492-5.