Chemokine CCL2

"Chemokine CCL2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.

Descriptor ID	D018932
MeSH Number(s)	D12.644.276.374.200.110.990.600 D12.776.467.374.200.110.990.600 D23.125.300.110.990.600 D23.469.200.110.990.600 D23.529.374.200.110.990.500
Concept/Terms	Chemokine CCL2 Chemokine CCL2 CCL2, Chemokine Monocyte Chemotactic and Activating Factor Monocyte Chemoattractant Protein-1 Chemoattractant Protein-1, Monocyte Monocyte Chemoattractant Protein 1 Chemokines CCL2 CCL2, Chemokines CCL2 Chemokine Chemokine, CCL2 Chemokine (C-C Motif) Ligand 2 Monocyte Chemotactic Protein-1 Chemotactic Protein-1, Monocyte Monocyte Chemotactic Protein 1

Below are MeSH descriptors whose meaning is more general than "Chemokine CCL2".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Chemokines [D12.644.276.374.200]
Chemokines, CC [D12.644.276.374.200.110]
Monocyte Chemoattractant Proteins [D12.644.276.374.200.110.990]
Chemokine CCL2 [D12.644.276.374.200.110.990.600]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Chemokines [D12.776.467.374.200]
Chemokines, CC [D12.776.467.374.200.110]
Monocyte Chemoattractant Proteins [D12.776.467.374.200.110.990]
Chemokine CCL2 [D12.776.467.374.200.110.990.600]
Biological Factors [D23]
Chemotactic Factors [D23.125]
Chemokines [D23.125.300]
Chemokines, CC [D23.125.300.110]
Monocyte Chemoattractant Proteins [D23.125.300.110.990]
Chemokine CCL2 [D23.125.300.110.990.600]
Inflammation Mediators [D23.469]
Chemokines [D23.469.200]
Chemokines, CC [D23.469.200.110]
Monocyte Chemoattractant Proteins [D23.469.200.110.990]
Chemokine CCL2 [D23.469.200.110.990.600]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Chemokines [D23.529.374.200]
Chemokines, CC [D23.529.374.200.110]
Monocyte Chemoattractant Proteins [D23.529.374.200.110.990]
Chemokine CCL2 [D23.529.374.200.110.990.500]

Below are MeSH descriptors whose meaning is related to "Chemokine CCL2".

Below are MeSH descriptors whose meaning is more specific than "Chemokine CCL2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Chemokine CCL2" by people in this website by year, and whether "Chemokine CCL2" was a major or minor topic of these publications.

Bar chart showing 26 publications over 16 distinct years, with a maximum of 3 publications in 2005 and 2009 and 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	0	1	1
2004	0	1	1
2005	2	1	3
2006	1	1	2
2007	0	1	1
2008	1	0	1
2009	2	1	3
2010	1	2	3
2011	1	0	1
2012	1	1	2
2013	0	2	2
2014	1	0	1
2017	1	0	1
2018	0	2	2
2025	0	1	1

Below are the most recent publications written about "Chemokine CCL2" by people in Profiles.

Anderson WA, Domingo-Relloso A, Galvez-Fernandez M, Schilling K, Glabonjat RA, Basu A, Nigra AE, Gutierrez OM, Scherzer R, Goldsmith J, Sarnak MJ, Bonventre JV, Kimmel PL, Vasan RS, Ix JH, Shlipak MG, Navas-Acien A. Uranium exposure and kidney tubule biomarkers in the Multi-Ethnic Study of Atherosclerosis (MESA). Environ Res. 2025 Apr 15; 271:121060.

View in: PubMed
Roedig H, Nastase MV, Frey H, Moreth K, Zeng-Brouwers J, Poluzzi C, Hsieh LT, Brandts C, Fulda S, Wygrecka M, Schaefer L. Biglycan is a new high-affinity ligand for CD14 in macrophages. Matrix Biol. 2019 04; 77:4-22.

View in: PubMed
Ezquer F, Morales P, Quintanilla ME, Santapau D, Lespay-Rebolledo C, Ezquer M, Herrera-Marschitz M, Israel Y. Intravenous administration of anti-inflammatory mesenchymal stem cell spheroids reduces chronic alcohol intake and abolishes binge-drinking. Sci Rep. 2018 03 22; 8(1):4325.

View in: PubMed
Hsieh LT, Nastase MV, Roedig H, Zeng-Brouwers J, Poluzzi C, Schwalm S, Fork C, Tredup C, Brandes RP, Wygrecka M, Huwiler A, Pfeilschifter J, Schaefer L. Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants. Int J Mol Sci. 2017 Mar 09; 18(3).

View in: PubMed
Grisanti LA, Repas AA, Talarico JA, Gold JI, Carter RL, Koch WJ, Tilley DG. Temporal and gefitinib-sensitive regulation of cardiac cytokine expression via chronic ?-adrenergic receptor stimulation. Am J Physiol Heart Circ Physiol. 2015 Feb 15; 308(4):H316-30.

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Baudrand R, Lian CG, Lian BQ, Ricchiuti V, Yao TM, Li J, Williams GH, Adler GK. Long-term dietary sodium restriction increases adiponectin expression and ameliorates the proinflammatory adipokine profile in obesity. Nutr Metab Cardiovasc Dis. 2014 Jan; 24(1):34-41.

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Bocian C, Urbanowitz AK, Owens RT, Iozzo RV, G?tte M, Seidler DG. Decorin potentiates interferon-? activity in a model of allergic inflammation. J Biol Chem. 2013 May 03; 288(18):12699-711.

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Ocuin LM, Zeng S, Cavnar MJ, Sorenson EC, Bamboat ZM, Greer JB, Kim TS, Popow R, DeMatteo RP. Nilotinib protects the murine liver from ischemia/reperfusion injury. J Hepatol. 2012 Oct; 57(4):766-73.

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Malon JT, Maddula S, Bell H, Cao L. Involvement of calcitonin gene-related peptide and CCL2 production in CD40-mediated behavioral hypersensitivity in a model of neuropathic pain. Neuron Glia Biol. 2011 May; 7(2-4):117-28.

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Tulipan JE, Stone J, Samstein B, Kato T, Emond JC, Henry SD, Guarrera JV. Molecular expression of acute phase mediators is attenuated by machine preservation in human liver transplantation: preliminary analysis of effluent, serum, and liver biopsies. Surgery. 2011 Aug; 150(2):352-60.

View in: PubMed

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