"Haptens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small antigenic determinants capable of eliciting an immune response only when coupled to a carrier. Haptens bind to antibodies but by themselves cannot elicit an antibody response.
| Descriptor ID |
D006241
|
| MeSH Number(s) |
D23.050.550.480
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Haptens".
Below are MeSH descriptors whose meaning is more specific than "Haptens".
This graph shows the total number of publications written about "Haptens" by people in this website by year, and whether "Haptens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 3 | 3 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Haptens" by people in Profiles.
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Erkes DA, Selvan SR. Hapten-induced contact hypersensitivity, autoimmune reactions, and tumor regression: plausibility of mediating antitumor immunity. J Immunol Res. 2014; 2014:175265.
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Mahipal A, Terai M, Berd D, Chervoneva I, Patel K, Mastrangelo MJ, Sato T. Tumor-derived interleukin-10 as a prognostic factor in stage III patients undergoing adjuvant treatment with an autologous melanoma cell vaccine. Cancer Immunol Immunother. 2011 Jul; 60(7):1039-45.
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Alabyev B, Vuyyuru R, Manser T. Influence of Fas on the regulation of the response of an anti-nuclear antigen B cell clonotype to foreign antigen. Int Immunol. 2008 Oct; 20(10):1279-87.
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Coffey F, Liu X, Manser T. Primary development and participation in a foreign antigen-driven immune response of a chromatin-reactive B cell clonotype are not influenced by TLR9 or other MyD88-dependent TLRs. J Immunol. 2007 Nov 15; 179(10):6663-72.
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Notidis E, Heltemes L, Manser T. Dominant, hierarchical induction of peripheral tolerance during foreign antigen-driven B cell development. Immunity. 2002 Sep; 17(3):317-27.
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Dasgupta A, Kesari KV, Ramaswamy KK, Amenta PS, Das KM. Oral administration of unmodified colonic but not small intestinal antigens protects rats from hapten-induced colitis. Clin Exp Immunol. 2001 Jul; 125(1):41-7.
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Hoch S, Boyd M, Malone B, Gonye G, Schwaber J, Schwaber J. Fas-mediated apoptosis eliminates B cells that acquire self-reactivity during the germinal center response to NP. Cell Immunol. 2000 Aug 01; 203(2):103-10.
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DeSilva BS, Orosz G, Egodage KL, Carlson RG, Schowen RL, Wilson GS. Catalytic antibodies for complex reactions: hapten design and the importance of screening for catalysis in the generation of catalytic antibodies for the NDA/CN reaction. Appl Biochem Biotechnol. 2000 Jan-Mar; 83(1-3):195-206; discussion 206-8, 297-313.
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Vora KA, Tumas-Brundage K, Manser T. Contrasting the in situ behavior of a memory B cell clone during primary and secondary immune responses. J Immunol. 1999 Oct 15; 163(8):4315-27.
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De Silva BS, Egodage KL, Wilson GS. Purified protein derivative (PPD) as an immunogen carrier elicits high antigen specificity to haptens. Bioconjug Chem. 1999 May-Jun; 10(3):496-501.