Angiopoietin-1

"Angiopoietin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The first to be discovered member of the angiopoietin family. It may play a role in increasing the sprouting and branching of BLOOD VESSELS. Angiopoietin-1 specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of angiopoietin-1 occur due to ALTERNATIVE SPLICING of its mRNA.

Descriptor ID	D042683
MeSH Number(s)	D12.644.276.100.100.100 D12.776.467.100.100.100 D23.529.100.100.100
Concept/Terms	Angiopoietin-1 Angiopoietin-1 Angiopoietin 1

Below are MeSH descriptors whose meaning is more general than "Angiopoietin-1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Angiogenic Proteins [D12.644.276.100]
Angiopoietins [D12.644.276.100.100]
Angiopoietin-1 [D12.644.276.100.100.100]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Angiogenic Proteins [D12.776.467.100]
Angiopoietins [D12.776.467.100.100]
Angiopoietin-1 [D12.776.467.100.100.100]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Angiogenic Proteins [D23.529.100]
Angiopoietins [D23.529.100.100]
Angiopoietin-1 [D23.529.100.100.100]

Below are MeSH descriptors whose meaning is related to "Angiopoietin-1".

Below are MeSH descriptors whose meaning is more specific than "Angiopoietin-1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Angiopoietin-1" by people in this website by year, and whether "Angiopoietin-1" was a major or minor topic of these publications.

Bar chart showing 6 publications over 4 distinct years, with a maximum of 3 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2011	1	0	1
2012	2	1	3
2017	1	0	1
2023	0	1	1

Below are the most recent publications written about "Angiopoietin-1" by people in Profiles.

Atreya MR, Cvijanovich NZ, Fitzgerald JC, Weiss SL, Bigham MT, Jain PN, Schwarz AJ, Lutfi R, Nowak J, Allen GL, Thomas NJ, Grunwell JR, Baines T, Quasney M, Haileselassie B, Alder MN, Lahni P, Ripberger S, Ekunwe A, Campbell KR, Walley KR, Standage SW. Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1. Crit Care. 2023 06 26; 27(1):250.

View in: PubMed
Syed M, Das P, Pawar A, Aghai ZH, Kaskinen A, Zhuang ZW, Ambalavanan N, Pryhuber G, Andersson S, Bhandari V. Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs. Nat Commun. 2017 10 27; 8(1):1173.

View in: PubMed
Ngok SP, Geyer R, Liu M, Kourtidis A, Agrawal S, Wu C, Seerapu HR, Lewis-Tuffin LJ, Moodie KL, Huveldt D, Marx R, Baraban JM, Storz P, Horowitz A, Anastasiadis PZ. VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx. J Cell Biol. 2012 Dec 24; 199(7):1103-15.

View in: PubMed
Dai J, Wan S, Zhou F, Myers RE, Guo X, Li B, Fu X, Palazzo JP, Dou K, Yang H, Xing J. Genetic polymorphism in a VEGF-independent angiogenesis gene ANGPT1 and overall survival of colorectal cancer patients after surgical resection. PLoS One. 2012; 7(4):e34758.

View in: PubMed
Sakai D, Nakamura Y, Nakai T, Mishima T, Kato S, Grad S, Alini M, Risbud MV, Chan D, Cheah KS, Yamamura K, Masuda K, Okano H, Ando K, Mochida J. Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc. Nat Commun. 2012; 3:1264.

View in: PubMed
Fuxe J, Tabruyn S, Colton K, Zaid H, Adams A, Baluk P, Lashnits E, Morisada T, Le T, O'Brien S, Epstein DM, Koh GY, McDonald DM. Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation. Am J Pathol. 2011 Jun; 178(6):2897-909.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement