Receptor, Serotonin, 5-HT1A
"Receptor, Serotonin, 5-HT1A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found distributed through the CENTRAL NERVOUS SYSTEM where they are involved in neuroendocrine regulation of ACTH secretion. The fact that this serotonin receptor subtype is particularly sensitive to SEROTONIN RECEPTOR AGONISTS such as BUSPIRONE suggests its role in the modulation of ANXIETY and DEPRESSION.
| Descriptor ID |
D044282
|
| MeSH Number(s) |
D12.776.543.750.670.800.100.100 D12.776.543.750.695.800.100.100 D12.776.543.750.720.850.100.100
|
| Concept/Terms |
Receptor, Serotonin, 5-HT1A- Receptor, Serotonin, 5-HT1A
- 5-HT1A Receptor
- 5 HT1A Receptor
- Receptor, 5-HT1A
- 5-Hydroxytryptamine 1A Receptor
- 1A Receptor, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 1A Receptor
- 5-Hydroxytryptamine 1A Receptors
- 1A Receptors, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 1A Receptors
- Receptors, 5-Hydroxytryptamine 1A
- Serotonin, 5-HT1a Receptor
- 5-HT1a Receptor Serotonin
- Receptor Serotonin, 5-HT1a
- Serotonin, 5 HT1a Receptor
- Serotonin 1A Receptor
- Receptor, Serotonin 1A
- Serotonin Receptor, 5-HT1A
- 5-HT1A Serotonin Receptor
- Receptor, 5-HT1A Serotonin
- Serotonin Receptor, 5 HT1A
- 5-HT(1A) Receptor
- Receptor, 5-Hydroxytryptamine 1A
- Receptor, 5 Hydroxytryptamine 1A
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT1A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Serotonin [D12.776.543.750.670.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.670.800.100]
- Receptor, Serotonin, 5-HT1A [D12.776.543.750.670.800.100.100]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Serotonin [D12.776.543.750.695.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.695.800.100]
- Receptor, Serotonin, 5-HT1A [D12.776.543.750.695.800.100.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Serotonin [D12.776.543.750.720.850]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.720.850.100]
- Receptor, Serotonin, 5-HT1A [D12.776.543.750.720.850.100.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT1A".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT1A" by people in this website by year, and whether "Receptor, Serotonin, 5-HT1A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Receptor, Serotonin, 5-HT1A" by people in Profiles.
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Yi L, Sun H, Zhang H, Chen Y, Zhou L, Xuan L, Zhan T, Jiang Y, Xu S. Down-regulation of HTR1A-modulated ACC activation contributes to stress-induced visceral hyperalgesia in rats. Neurogastroenterol Motil. 2019 08; 31(8):e13620.
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Ward SJ, McAllister SD, Kawamura R, Murase R, Neelakantan H, Walker EA. Cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT(1A) receptors without diminishing nervous system function or chemotherapy efficacy. Br J Pharmacol. 2014 Feb; 171(3):636-45.
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Shen F, Cheng L, Douglas AE, Riobo NA, Manning DR. Smoothened is a fully competent activator of the heterotrimeric G protein G(i). Mol Pharmacol. 2013 Mar; 83(3):691-7.
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Kline AE, Olsen AS, Sozda CN, Hoffman AN, Cheng JP. Evaluation of a combined treatment paradigm consisting of environmental enrichment and the 5-HT1A receptor agonist buspirone after experimental traumatic brain injury. J Neurotrauma. 2012 Jul 01; 29(10):1960-9.
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Drossman DA, Danilewitz M, Naesdal J, Hwang C, Adler J, Silberg DG. Randomized, double-blind, placebo-controlled trial of the 5-HT1A receptor antagonist AZD7371 tartrate monohydrate (robalzotan tartrate monohydrate) in patients with irritable bowel syndrome. Am J Gastroenterol. 2008 Oct; 103(10):2562-9.
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Beyer CE, Ghavami A, Lin Q, Sung A, Rhodes KJ, Dawson LA, Schechter LE, Young KH. Regulators of G-protein signaling 4: modulation of 5-HT1A-mediated neurotransmitter release in vivo. Brain Res. 2004 Oct 01; 1022(1-2):214-20.