Ubiquitin-Conjugating Enzymes
"Ubiquitin-Conjugating Enzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of enzymes that form a thioester bond to UBIQUITIN with the assistance of UBIQUITIN-ACTIVATING ENZYMES. They transfer ubiquitin to the LYSINE of a substrate protein with the assistance of UBIQUITIN-PROTEIN LIGASES.
| Descriptor ID |
D044763
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| MeSH Number(s) |
D08.811.464.938.500
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| Concept/Terms |
Ubiquitin-Conjugating Enzymes- Ubiquitin-Conjugating Enzymes
- Enzymes, Ubiquitin-Conjugating
- Ubiquitin Conjugating Enzymes
- Ubiquitin-Conjugating Enzyme E2
- E2, Ubiquitin-Conjugating Enzyme
- Enzyme E2, Ubiquitin-Conjugating
- Ubiquitin Conjugating Enzyme E2
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Below are MeSH descriptors whose meaning is more general than "Ubiquitin-Conjugating Enzymes".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitin-Conjugating Enzymes".
This graph shows the total number of publications written about "Ubiquitin-Conjugating Enzymes" by people in this website by year, and whether "Ubiquitin-Conjugating Enzymes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ubiquitin-Conjugating Enzymes" by people in Profiles.
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Zhou J, Xu Y, Lin S, Guo Y, Deng W, Zhang Y, Guo A, Xue Y. iUUCD 2.0: an update with rich annotations for ubiquitin and ubiquitin-like conjugations. Nucleic Acids Res. 2018 01 04; 46(D1):D447-D453.
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Czeschik JC, Bauer P, Buiting K, Dufke C, Guill?n-Navarro E, Johnson DS, Koehler U, L?pez-Gonz?lez V, L?decke HJ, Male A, Morrogh D, Rie? A, Tzschach A, Wieczorek D, Kuechler A. X-linked intellectual disability type Nascimento is a clinically distinct, probably underdiagnosed entity. Orphanet J Rare Dis. 2013 Sep 21; 8:146.
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Codding JA, Israel BA, Thorpe C. Protein substrate discrimination in the quiescin sulfhydryl oxidase (QSOX) family. Biochemistry. 2012 May 22; 51(20):4226-35.
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de Leeuw N, Bulk S, Green A, Jaeckle-Santos L, Baker LA, Zinn AR, Kleefstra T, van der Smagt JJ, Vianne Morgante AM, de Vries BB, van Bokhoven H, de Brouwer AP. UBE2A deficiency syndrome: Mild to severe intellectual disability accompanied by seizures, absent speech, urogenital, and skin anomalies in male patients. Am J Med Genet A. 2010 Dec; 152A(12):3084-90.
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Ivanov AV, Peng H, Yurchenko V, Yap KL, Negorev DG, Schultz DC, Psulkowski E, Fredericks WJ, White DE, Maul GG, Sadofsky MJ, Zhou MM, Rauscher FJ. PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing. Mol Cell. 2007 Dec 14; 28(5):823-37.
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Adachi K, Lakka V, Zhao Y, Surrey S. Ubiquitylation of nascent globin chains in a cell-free system. J Biol Chem. 2004 Oct 01; 279(40):41767-74.