Phosphoglycerate Dehydrogenase
"Phosphoglycerate Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the oxidation of 3-phosphoglycerate to 3-phosphohydroxypyruvate. It takes part in the L-SERINE biosynthesis pathway.
| Descriptor ID |
D050543
|
| MeSH Number(s) |
D08.811.682.047.150.650
|
| Concept/Terms |
Phosphoglycerate Dehydrogenase- Phosphoglycerate Dehydrogenase
- Dehydrogenase, Phosphoglycerate
- Phosphoglycerate Oxidoreductase
- Oxidoreductase, Phosphoglycerate
- D-3-Phosphoglycerate Dehydrogenase
- D 3 Phosphoglycerate Dehydrogenase
- Dehydrogenase, D-3-Phosphoglycerate
- 3-Phosphoglycerate Dehydrogenase
- 3 Phosphoglycerate Dehydrogenase
- Dehydrogenase, 3-Phosphoglycerate
- 3-Phosphoglycerate-NAD+ 2-Oxidoreductase
- 2-Oxidoreductase, 3-Phosphoglycerate-NAD+
- 3 Phosphoglycerate NAD+ 2 Oxidoreductase
|
Below are MeSH descriptors whose meaning is more general than "Phosphoglycerate Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Phosphoglycerate Dehydrogenase".
This graph shows the total number of publications written about "Phosphoglycerate Dehydrogenase" by people in this website by year, and whether "Phosphoglycerate Dehydrogenase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Phosphoglycerate Dehydrogenase" by people in Profiles.
-
Nguyen MQ, Teh JLF, Purwin TJ, Chervoneva I, Davies MA, Nathanson KL, Cheng PF, Levesque MP, Dummer R, Aplin AE. Targeting PHGDH Upregulation Reduces Glutathione Levels and Resensitizes Resistant NRAS-Mutant Melanoma to MAPK Kinase Inhibition. J Invest Dermatol. 2020 11; 140(11):2242-2252.e7.
-
Dalton WB, Helmenstine E, Walsh N, Gondek LP, Kelkar DS, Read A, Natrajan R, Christenson ES, Roman B, Das S, Zhao L, Leone RD, Shinn D, Groginski T, Madugundu AK, Patil A, Zabransky DJ, Medford A, Lee J, Cole AJ, Rosen M, Thakar M, Ambinder A, Donaldson J, DeZern AE, Cravero K, Chu D, Madero-Marroquin R, Pandey A, Hurley PJ, Lauring J, Park BH. Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation. J Clin Invest. 2019 08 08; 129(11):4708-4723.
-
Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, Barretina J, Kalaany NY, Hsu PP, Ottina K, Chan AM, Yuan B, Garraway LA, Root DE, Mino-Kenudson M, Brachtel EF, Driggers EM, Sabatini DM. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature. 2011 Aug 18; 476(7360):346-50.