G1 Phase Cell Cycle Checkpoints
"G1 Phase Cell Cycle Checkpoints" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory signaling systems that control the progression of the CELL CYCLE through the G1 PHASE and allow transition to S PHASE when the cells are ready to undergo DNA REPLICATION. DNA DAMAGE, or the deficiencies in specific cellular components or nutrients may cause the cells to halt before progressing through G1 phase.
| Descriptor ID |
D059585
|
| MeSH Number(s) |
G04.144.109.249 G04.144.500.320.500
|
| Concept/Terms |
G1 Phase Cell Cycle Checkpoints- G1 Phase Cell Cycle Checkpoints
- G1 Phase Checkpoints
- Checkpoint, G1 Phase
- Checkpoints, G1 Phase
- G1 Phase Checkpoint
- G1 Cell Cycle Checkpoints
G1 Phase Restriction Point- G1 Phase Restriction Point
- G1 Restriction Point
- G1 Restriction Points
- Restriction Point, G1
- Restriction Points, G1
|
Below are MeSH descriptors whose meaning is more general than "G1 Phase Cell Cycle Checkpoints".
Below are MeSH descriptors whose meaning is more specific than "G1 Phase Cell Cycle Checkpoints".
This graph shows the total number of publications written about "G1 Phase Cell Cycle Checkpoints" by people in this website by year, and whether "G1 Phase Cell Cycle Checkpoints" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "G1 Phase Cell Cycle Checkpoints" by people in Profiles.
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Li F, Mladenov E, Dueva R, Stuschke M, Timmermann B, Iliakis G. Shift in G1-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation. Cells. 2021 12 27; 11(1).
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Taubenberger AV, Girardo S, Tr?ber N, Fischer-Friedrich E, Kr?ter M, Wagner K, Kurth T, Richter I, Haller B, Binner M, Hahn D, Freudenberg U, Werner C, Guck J. 3D Microenvironment Stiffness Regulates Tumor Spheroid Growth and Mechanics via p21 and ROCK. Adv Biosyst. 2019 09; 3(9):e1900128.
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Trousil S, Kaliszczak M, Schug Z, Nguyen QD, Tomasi G, Favicchio R, Brickute D, Fortt R, Twyman FJ, Carroll L, Kalusa A, Navaratnam N, Adejumo T, Carling D, Gottlieb E, Aboagye EO. The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth. Oncotarget. 2016 Jun 14; 7(24):37103-37120.
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Benedetti E, Antonosante A, d'Angelo M, Cristiano L, Galzio R, Destouches D, Florio TM, Dhez AC, Astarita C, Cinque B, Fidoamore A, Rosati F, Cifone MG, Ippoliti R, Giordano A, Courty J, Cimini A. Nucleolin antagonist triggers autophagic cell death in human glioblastoma primary cells and decreased in vivo tumor growth in orthotopic brain tumor model. Oncotarget. 2015 Dec 08; 6(39):42091-104.
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Sampson VB, Vetter NS, Kamara DF, Collier AB, Gresh RC, Kolb EA. Vorinostat Enhances Cytotoxicity of SN-38 and Temozolomide in Ewing Sarcoma Cells and Activates STAT3/AKT/MAPK Pathways. PLoS One. 2015; 10(11):e0142704.
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Yan G, Lanza-Jacoby S, Wang C. Nexrutine inhibits survival and induces G1 cell cycle arrest, which is associated with apoptosis or autophagy depending on the breast cancer cell line. Nutr Cancer. 2014; 66(3):506-16.
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Shao Y, Aplin AE. BH3-only protein silencing contributes to acquired resistance to PLX4720 in human melanoma. Cell Death Differ. 2012 Dec; 19(12):2029-39.