Voltage-Gated Sodium Channel beta-1 Subunit
"Voltage-Gated Sodium Channel beta-1 Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A voltage-gated sodium channel beta subunit abundantly expressed in SKELETAL MUSCLE; HEART; and BRAIN. It non-covalently associates with voltage-gated alpha subunits. Defects in the SCN1B gene, which codes for this beta subunit, are associated with generalized epilepsy with febrile seizures plus, type 1, and Brugada syndrome 5.
| Descriptor ID |
D062547
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| MeSH Number(s) |
D12.776.157.530.400.875.750.960.100 D12.776.543.550.450.875.750.970.100 D12.776.543.585.400.875.750.970.100 D12.776.631.960.970.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Voltage-Gated Sodium Channel beta-1 Subunit".
Below are MeSH descriptors whose meaning is more specific than "Voltage-Gated Sodium Channel beta-1 Subunit".
This graph shows the total number of publications written about "Voltage-Gated Sodium Channel beta-1 Subunit" by people in this website by year, and whether "Voltage-Gated Sodium Channel beta-1 Subunit" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Voltage-Gated Sodium Channel beta-1 Subunit" by people in Profiles.
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Sarica AS, Bor S, Orman MN, Barajas-Martinez H, Juang JJ, Antzelevitch C, Hasdemir C. Frequency of Irritable Bowel Syndrome in Patients with Brugada Syndrome and Drug-Induced Type 1 Brugada Pattern. Am J Cardiol. 2021 07 15; 151:51-56.
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Hasdemir C, Payzin S, Kocabas U, Sahin H, Yildirim N, Alp A, Aydin M, Pfeiffer R, Burashnikov E, Wu Y, Antzelevitch C. High prevalence of concealed Brugada syndrome in patients with atrioventricular nodal reentrant tachycardia. Heart Rhythm. 2015 Jul; 12(7):1584-94.
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Hu D, Barajas-Mart?nez H, Medeiros-Domingo A, Crotti L, Veltmann C, Schimpf R, Urrutia J, Alday A, Casis O, Pfeiffer R, Burashnikov E, Caceres G, Tester DJ, Wolpert C, Borggrefe M, Schwartz P, Ackerman MJ, Antzelevitch C. A novel rare variant in SCN1Bb linked to Brugada syndrome and SIDS by combined modulation of Na(v)1.5 and K(v)4.3 channel currents. Heart Rhythm. 2012 May; 9(5):760-9.