"Occludin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MARVEL domain protein that binds to and regulates PROTEIN PHOSPHATASE 1. Occludin plays an important role in the formation and regulation of the TIGHT JUNCTION paracellular permeability barrier.
| Descriptor ID |
D062793
|
| MeSH Number(s) |
D12.776.543.488.500 D12.776.543.940.750
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Occludin".
Below are MeSH descriptors whose meaning is more specific than "Occludin".
This graph shows the total number of publications written about "Occludin" by people in this website by year, and whether "Occludin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Occludin" by people in Profiles.
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Yan Z, Wang C, Meng Z, Gan L, Guo R, Liu J, Bond Lau W, Xie D, Zhao J, Lopez BL, Christopher TA, Naik UP, Ma X, Wang Y. C1q/TNF-Related Protein 3 Prevents Diabetic Retinopathy via AMPK-Dependent Stabilization of Blood-Retinal Barrier Tight Junctions. Cells. 2022 02 23; 11(5).
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Bilal S, Jaggi S, Janosevic D, Shah N, Teymour S, Voronina A, Watari J, Axis J, Amsler K. ZO-1 protein is required for hydrogen peroxide to increase MDCK cell paracellular permeability in an ERK 1/2-dependent manner. Am J Physiol Cell Physiol. 2018 09 01; 315(3):C422-C431.
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Lin JE, Snook AE, Li P, Stoecker BA, Kim GW, Magee MS, Garcia AV, Valentino MA, Hyslop T, Schulz S, Waldman SA. GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity. PLoS One. 2012; 7(2):e31686.
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Rajasekaran SA, Barwe SP, Gopal J, Ryazantsev S, Schneeberger EE, Rajasekaran AK. Na-K-ATPase regulates tight junction permeability through occludin phosphorylation in pancreatic epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2007 Jan; 292(1):G124-33.
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Rendon-Huerta E, Valenzano MC, Mullin JM, Trembeth SE, Kothari R, Hameed B, Mercogliano G, Thornton JJ. Comparison of three integral tight junction barrier proteins in Barrett's epithelium versus normal esophageal epithelium. Am J Gastroenterol. 2003 Aug; 98(8):1901-3.