Synaptophysin

"Synaptophysin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A MARVEL domain-containing protein found in the presynaptic vesicles of NEURONS and NEUROENDOCRINE CELLS. It is commonly used as an immunocytochemical marker for neuroendocrine differentiation.

Descriptor ID	D016708
MeSH Number(s)	D12.776.543.488.875 D12.776.543.990.840 D12.776.631.800 D23.101.140.800
Concept/Terms	Synaptophysin Synaptophysin p38 Membrane Protein, Synaptic Vesicle

Below are MeSH descriptors whose meaning is more general than "Synaptophysin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
MARVEL Domain-Containing Proteins [D12.776.543.488]
Synaptophysin [D12.776.543.488.875]
Vesicular Transport Proteins [D12.776.543.990]
Synaptophysin [D12.776.543.990.840]
Nerve Tissue Proteins [D12.776.631]
Synaptophysin [D12.776.631.800]
Biological Factors [D23]
Biomarkers [D23.101]
Biomarkers, Tumor [D23.101.140]
Synaptophysin [D23.101.140.800]

Below are MeSH descriptors whose meaning is related to "Synaptophysin".

Below are MeSH descriptors whose meaning is more specific than "Synaptophysin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Synaptophysin" by people in this website by year, and whether "Synaptophysin" was a major or minor topic of these publications.

Bar chart showing 8 publications over 6 distinct years, with a maximum of 2 publications in 1998 and 2021

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1998	2	2
2000	1	1
2003	1	1
2011	1	1
2021	2	2
2024	1	1

Below are the most recent publications written about "Synaptophysin" by people in Profiles.

Naranjo NM, Kennedy A, Testa A, Verrillo CE, Altieri AD, Kean R, Hooper DC, Yu J, Zhao J, Abinader O, Pickles MW, Hawkins A, Kelly WK, Mitra R, Languino LR. Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma. Cancer Biol Ther. 2024 12 31; 25(1):2364433.

View in: PubMed
Qu S, Fetsch P, Thomas A, Pommier Y, Schrump DS, Miettinen MM, Chen H. Molecular Subtypes of Primary SCLC Tumors and Their Associations With Neuroendocrine and Therapeutic Markers. J Thorac Oncol. 2022 01; 17(1):141-153.

View in: PubMed
Quaglia F, Krishn SR, Wang Y, Goodrich DW, McCue P, Kossenkov AV, Mandigo AC, Knudsen KE, Weinreb PH, Corey E, Kelly WK, Languino LR. Differential expression of aV?3 and aV?6 integrins in prostate cancer progression. PLoS One. 2021; 16(1):e0244985.

View in: PubMed
Knoepp SM, Hookim K, Placido J, Fields KL, Roh MH. The application of immunocytochemistry to cytologic direct smears of metastatic merkel cell carcinoma. Diagn Cytopathol. 2013 Aug; 41(8):729-33.

View in: PubMed
Kaya B, Mena H, Miettinen M, Rushing EJ. Alpha-internexin expression in medulloblastomas and atypical teratoid-rhabdoid tumors. Clin Neuropathol. 2003 Sep-Oct; 22(5):215-21.

View in: PubMed
Eagle RC, Ehya H, Shields JA, Shields CL. Choroidal metastasis as the initial manifestation of a pigmented neuroendocrine tumor. Arch Ophthalmol. 2000 Jun; 118(6):841-5.

View in: PubMed
Iczkowski KA, Bostwick DG, Roche PC, Cheville JC. Inhibin A is a sensitive and specific marker for testicular sex cord-stromal tumors. Mod Pathol. 1998 Aug; 11(8):774-9.

View in: PubMed
Yonekawa Y, Harada A, Okada Y, Funakoshi T, Kanai Y, Takei Y, Terada S, Noda T, Hirokawa N. Defect in synaptic vesicle precursor transport and neuronal cell death in KIF1A motor protein-deficient mice. J Cell Biol. 1998 Apr 20; 141(2):431-41.

View in: PubMed
O'Hara BJ, McCue PA, Miettinen M. Bile duct adenomas with endocrine component. Immunohistochemical study and comparison with conventional bile duct adenomas. Am J Surg Pathol. 1992 Jan; 16(1):21-5.

View in: PubMed
Miettinen M. Synaptophysin and neurofilament proteins as markers for neuroendocrine tumors. Arch Pathol Lab Med. 1987 Sep; 111(9):813-8.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement