Alcohol Dehydrogenase

"Alcohol Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A zinc-containing enzyme which oxidizes primary and secondary alcohols or hemiacetals in the presence of NAD. In alcoholic fermentation, it catalyzes the final step of reducing an aldehyde to an alcohol in the presence of NADH and hydrogen.

Descriptor ID	D000426
MeSH Number(s)	D08.811.682.047.820.250
Concept/Terms	Alcohol Dehydrogenase Alcohol Dehydrogenase Dehydrogenase, Alcohol Alcohol-NAD+ Oxidoreductase Alcohol NAD+ Oxidoreductase Oxidoreductase, Alcohol-NAD+ Alcohol Dehydrogenase (NAD+) Alcohol Dehydrogenase II Alcohol Dehydrogenase II Yeast Alcohol Dehydrogenase Yeast Alcohol Dehydrogenase Alcohol Dehydrogenase, Yeast Dehydrogenase, Yeast Alcohol Alcohol Dehydrogenase I Alcohol Dehydrogenase I

Below are MeSH descriptors whose meaning is more general than "Alcohol Dehydrogenase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Oxidoreductases [D08.811.682]
Alcohol Oxidoreductases [D08.811.682.047]
NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases [D08.811.682.047.820]
Alcohol Dehydrogenase [D08.811.682.047.820.250]

Below are MeSH descriptors whose meaning is related to "Alcohol Dehydrogenase".

Below are MeSH descriptors whose meaning is more specific than "Alcohol Dehydrogenase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Alcohol Dehydrogenase" by people in this website by year, and whether "Alcohol Dehydrogenase" was a major or minor topic of these publications.

Bar chart showing 11 publications over 10 distinct years, with a maximum of 2 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
2002	0	1	1
2004	1	0	1
2007	1	0	1
2008	0	1	1
2009	1	0	1
2011	2	0	2
2012	1	0	1
2014	0	1	1
2024	0	1	1

Below are the most recent publications written about "Alcohol Dehydrogenase" by people in Profiles.

Flashner S, Shimonosono M, Tomita Y, Matsuura N, Ohashi S, Muto M, Klein-Szanto AJ, Alan Diehl J, Chen CH, Mochly-Rosen D, Weinberg KI, Nakagawa H. ALDH2 dysfunction and alcohol cooperate in cancer stem cell enrichment. Carcinogenesis. 2024 02 12; 45(1-2):95-106.

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Romero F, Shah D, Duong M, Stafstrom W, Hoek JB, Kallen CB, Lang CH, Summer R. Chronic alcohol ingestion in rats alters lung metabolism, promotes lipid accumulation, and impairs alveolar macrophage functions. Am J Respir Cell Mol Biol. 2014 Dec; 51(6):840-9.

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Nagel ZD, Meadows CW, Dong M, Bahnson BJ, Klinman JP. Active site hydrophobic residues impact hydrogen tunneling differently in a thermophilic alcohol dehydrogenase at optimal versus nonoptimal temperatures. Biochemistry. 2012 May 22; 51(20):4147-56.

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Karahanian E, Quintanilla ME, Tampier L, Rivera-Meza M, Bustamante D, Gonzalez-Lira V, Morales P, Herrera-Marschitz M, Israel Y. Ethanol as a prodrug: brain metabolism of ethanol mediates its reinforcing effects. Alcohol Clin Exp Res. 2011 Apr; 35(4):606-12.

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Israel Y, Rivera-Meza M, Quintanilla ME, Sapag A, Tampier L. Acetaldehyde burst protection of ADH1B*2 against alcoholism: an additional hormesis protection against esophageal cancers following alcohol consumption? Alcohol Clin Exp Res. 2011 May; 35(5):806-10.

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Rivera-Meza M, Quintanilla ME, Tampier L, Mura CV, Sapag A, Israel Y. Mechanism of protection against alcoholism by an alcohol dehydrogenase polymorphism: development of an animal model. FASEB J. 2010 Jan; 24(1):266-74.

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Tampier L, Quintanilla ME, Israel Y. Tolerance to disulfiram induced by chronic alcohol intake in the rat. Alcohol Clin Exp Res. 2008 Jun; 32(6):937-41.

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Quintanilla ME, Tampier L, Sapag A, Gerdtzen Z, Israel Y. Sex differences, alcohol dehydrogenase, acetaldehyde burst, and aversion to ethanol in the rat: a systems perspective. Am J Physiol Endocrinol Metab. 2007 Aug; 293(2):E531-7.

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Ceccarelli C, Liang ZX, Strickler M, Prehna G, Goldstein BM, Klinman JP, Bahnson BJ. Crystal structure and amide H/D exchange of binary complexes of alcohol dehydrogenase from Bacillus stearothermophilus: insight into thermostability and cofactor binding. Biochemistry. 2004 May 11; 43(18):5266-77.

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Werner J, Saghir M, Warshaw AL, Lewandrowski KB, Laposata M, Iozzo RV, Carter EA, Schatz RJ, Fern?ndez-Del Castillo C. Alcoholic pancreatitis in rats: injury from nonoxidative metabolites of ethanol. Am J Physiol Gastrointest Liver Physiol. 2002 Jul; 283(1):G65-73.

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