"Aldehyde Reductase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes reversibly the oxidation of an aldose to an alditol. It possesses broad specificity for many aldoses. EC 1.1.1.21.
| Descriptor ID |
D000449
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| MeSH Number(s) |
D08.811.682.047.150.700.156.500 D08.811.682.047.820.284.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aldehyde Reductase".
Below are MeSH descriptors whose meaning is more specific than "Aldehyde Reductase".
This graph shows the total number of publications written about "Aldehyde Reductase" by people in this website by year, and whether "Aldehyde Reductase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aldehyde Reductase" by people in Profiles.
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Johnson ZI, Doolittle AC, Snuggs JW, Shapiro IM, Le Maitre CL, Risbud MV. TNF-a promotes nuclear enrichment of the transcription factor TonEBP/NFAT5 to selectively control inflammatory but not osmoregulatory responses in nucleus pulposus cells. J Biol Chem. 2017 10 20; 292(42):17561-17575.
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Semmo N, Weber T, Idle JR, Beyoglu D. Metabolomics reveals that aldose reductase activity due to AKR1B10 is upregulated in hepatitis C virus infection. J Viral Hepat. 2015 Jul; 22(7):617-24.
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Nadkarni V, Gabbay KH, Bohren KM, Sheikh-Hamad D. Osmotic response element enhancer activity. Regulation through p38 kinase and mitogen-activated extracellular signal-regulated kinase kinase. J Biol Chem. 1999 Jul 16; 274(29):20185-90.
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Meyer WR, Doyle MB, Grifo JA, Lipetz KJ, Oates PJ, DeCherney AH, Diamond MP. Aldose reductase inhibition prevents galactose-induced ovarian dysfunction in the Sprague-Dawley rat. Am J Obstet Gynecol. 1992 Dec; 167(6):1837-43.
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Cerelli MJ, Curtis DL, Dunn JP, Nelson PH, Peak TM, Waterbury LD. Antiinflammatory and aldose reductase inhibitory activity of some tricyclic arylacetic acids. J Med Chem. 1986 Nov; 29(11):2347-51.