Aminoimidazole Carboxamide
"Aminoimidazole Carboxamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases.
| Descriptor ID |
D000620
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| MeSH Number(s) |
D03.383.129.308.030
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aminoimidazole Carboxamide".
Below are MeSH descriptors whose meaning is more specific than "Aminoimidazole Carboxamide".
This graph shows the total number of publications written about "Aminoimidazole Carboxamide" by people in this website by year, and whether "Aminoimidazole Carboxamide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aminoimidazole Carboxamide" by people in Profiles.
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Chatterjee A, Villarreal G, Oh DJ, Kang MH, Rhee DJ. AMP-activated protein kinase regulates intraocular pressure, extracellular matrix, and cytoskeleton in trabecular meshwork. Invest Ophthalmol Vis Sci. 2014 Apr 08; 55(5):3127-39.
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Dougherty MJ, Boyd JM, Downs DM. Inhibition of fructose-1,6-bisphosphatase by aminoimidazole carboxamide ribotide prevents growth of Salmonella enterica purH mutants on glycerol. J Biol Chem. 2006 Nov 10; 281(45):33892-9.