Ondansetron

"Ondansetron" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Descriptor ID	D017294
MeSH Number(s)	D03.383.129.308.690 D03.633.100.473.144.500 D03.633.300.148.500
Concept/Terms	Ondansetron Ondansetron Ondansetron, (+,-)-Isomer Ondansetron, (R)-Isomer Ondansetron, (R)-Isomer Ondansetron, (S)-Isomer Ondansetron, (S)-Isomer GR38032F GR38032F GR-38032F GR 38032F Zofran Zofran Ondansetron Hydrochloride Ondansetron Hydrochloride Hydrochloride, Ondansetron Ondansetron Monohydrochloride Monohydrochloride, Ondansetron Ondansetron Monohydrochloride Dihydrate Dihydrate, Ondansetron Monohydrochloride Monohydrochloride Dihydrate, Ondansetron SN-307 SN-307 SN 307 SN307

Below are MeSH descriptors whose meaning is more general than "Ondansetron".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azoles [D03.383.129]
Imidazoles [D03.383.129.308]
Ondansetron [D03.383.129.308.690]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Indoles [D03.633.100.473]
Carbazoles [D03.633.100.473.144]
Ondansetron [D03.633.100.473.144.500]
Heterocyclic Compounds, 3-Ring [D03.633.300]
Carbazoles [D03.633.300.148]
Ondansetron [D03.633.300.148.500]

Below are MeSH descriptors whose meaning is more specific than "Ondansetron".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ondansetron" by people in this website by year, and whether "Ondansetron" was a major or minor topic of these publications.

Bar chart showing 10 publications over 6 distinct years, with a maximum of 3 publications in 1996

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	3	0	3
2003	1	0	1
2007	1	0	1
2010	1	1	2
2014	1	0	1
2016	0	2	2

Below are the most recent publications written about "Ondansetron" by people in Profiles.

Singh PM, Borle A, Gouda D, Makkar JK, Arora MK, Trikha A, Sinha A, Goudra B. Efficacy of palonosetron in postoperative nausea and vomiting (PONV)-a meta-analysis. J Clin Anesth. 2016 Nov; 34:459-82.

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Boelig RC, Barton SJ, Saccone G, Kelly AJ, Edwards SJ, Berghella V. Interventions for treating hyperemesis gravidarum. Cochrane Database Syst Rev. 2016 May 11; (5):CD010607.

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Sinha AC, Singh PM, Williams NW, Ochroch EA, Goudra BG. Aprepitant's prophylactic efficacy in decreasing postoperative nausea and vomiting in morbidly obese patients undergoing bariatric surgery. Obes Surg. 2014 Feb; 24(2):225-31.

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DiIorio TM, Sharkey PF, Hewitt AM, Parvizi J. Antiemesis after total joint arthroplasty: does a single preoperative dose of aprepitant reduce nausea and vomiting? Clin Orthop Relat Res. 2010 Sep; 468(9):2405-9.

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Mraovic B, Simurina T. Matching groups for studying postoperative nausea and vomiting: should we care? Surg Endosc. 2010 Jul; 24(7):1796-7; author reply 1798-9.

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Antonetti M, Kirton O, Bui P, Ademi A, Staff I, Hudson-Civetta JA, Lilly R. The effects of preoperative rofecoxib, metoclopramide, dexamethasone, and ondansetron on postoperative pain and nausea in patients undergoing elective laparoscopic cholecystectomy. Surg Endosc. 2007 Oct; 21(10):1855-61.

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Blum RA, Majumdar A, McCrea J, Busillo J, Orlowski LH, Panebianco D, Hesney M, Petty KJ, Goldberg MR, Murphy MG, Gottesdiener KM, Hustad CM, Lates C, Kraft WK, Van Buren S, Waldman SA, Greenberg HE. Effects of aprepitant on the pharmacokinetics of ondansetron and granisetron in healthy subjects. Clin Ther. 2003 May; 25(5):1407-19.

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Khalil S, Rodarte A, Weldon BC, Weinstein M, Grunwald Z, Ginsberg B, Kaye R, Otto A, Wheeler M, Lawhorn CD, Prillaman BA, Creed M. Intravenous ondansetron in established postoperative emesis in children. S3A-381 Study Group. Anesthesiology. 1996 Aug; 85(2):270-6.

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Crucitt MA, Hyman W, Grote T, Tester W, Madajewicz S, Yee S, Wentz A, Griffin D, Parasuraman TV, Bryson J. Efficacy and tolerability of oral ondansetron versus prochlorperazine in the prevention of emesis associated with cyclophosphamide-based chemotherapy and maintenance of health-related quality of life. Clin Ther. 1996 Jul-Aug; 18(4):778-88.

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Crucitt MA, Hyman W, Grote T, Tester W, Madajewicz S, Yee S, Wentz A, Griffin D, Parasuraman TV, Bryson J. Efficacy and tolerability of oral ondansetron versus prochlorperazine in the prevention of emesis associated with cyclophosphamide-based chemotherapy and maintenance of health-related quality of life. Clin Ther. 1996 May-Jun; 18(3):508-18.

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